Dalpiciclib - Moligand™, ≥98% , Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6, CAS No.1637781-04-4, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6

CAS: 1637781-04-4 Cat. No.: D609727 분자식: C₂₅H₃₀N₆O₂ 분자량: 446.54

GRADE & PURITY Moligand™, ≥98%

Synonyms

6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperidin-4-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one | GTPL11189 | AKOS040759914 | EX-A5817 | Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino)- | DALP

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

동의어

6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperidin-4-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one | GTPL11189 | AKOS040759914 | EX-A5817 | Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino)- | DALP

사양 및 순도

Moligand™, ≥98%

생화학 및 생리적 메커니즘

Dalpiciclib (SHR-6390) is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4 nM and 9.9 nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhi

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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등급

Moligand™

작업 유형

INHIBITOR

작동 메커니즘

Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6

순수함

≥98%

이름과 식별자

• 분자량: 446.54

관련 대상(인간)

CDK4 Tclin Cyclin-dependent kinase 4 (0 Activities)

Discover Target: CDK4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CDK6 Tclin Cyclin-dependent kinase 6 (0 Activities)

Discover Target: CDK6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)