DBCO-NHCO-PEG4-NHS ester - ≥98% , CAS No.2100306-58-7

CAS: 2100306-58-7 Cat. No.: D596380 분자식: C₃₄H₃₉N₃O₁₀ 분자량: 649.69

등급 & 순도 ≥98%

Synonyms

DBCO-NHCO-PEG4-NHS | DBCO-NH-PEG4-NHS ester

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

Antibody Drug Conjugates(ADC), Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

개요

DBCO-NHCO-PEG4-NHS ester is a PEG derivative containing NHS ester that is able to react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and can also provide a long and flexible connection that minimizes steric hindrance during ligation. DBCO is commonly used for copper-free Click Chemistry reactions.

사양

동의어

DBCO-NHCO-PEG4-NHS | DBCO-NH-PEG4-NHS ester

사양 및 순도

≥98%

보관 조건

Protected from light,Store at -20°C,Argon charged

배송

Ice chest + Ice pads

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순수함

≥98%

이름과 식별자

Pubchem Sid

528764095

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528764095

이성체 SMILES

C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCC(=O)NCCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42

분자량

649.69

화학 및 물리적 특성

• 감도: Light sensitive；Moisture sensitive
• 분자량: 649.700 g/mol
• XLogP3: 0.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 20
• Exact Mass: 649.264 Da
• Monoisotopic Mass: 649.264 Da
• Topological Polar Surface Area: 150.000 Ų
• Heavy Atom Count: 47
• Formal Charge: 0
• Complexity: 1120.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1