Decamethonium Bromide - Moligand™, 10mM in DMSO , Muscle-type nicotinic acetylcholine receptor partial agonist, CAS No.541-22-0, Muscle-type nicotinic acetylcholine receptor partial agonist

CAS: 541-22-0 Cat. No.: D408329 분자식: C16H38Br2N2 분자량: 418.30 EC 번호: 208-772-2
주문 가능
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
1,10-Decanediaminium, N1,N1,N1,N10,N10,N10-hexamethyl-, bromide (1:2)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
USA
독일 (EU)*
Price
Qty
1ml
D408329-1ml
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US$27.90
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

Decamethonium Bromide is a nicotinicAChRpartial agonist andneuromuscularblocking agent.
In vitro

Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. Decamethonium, which has a short action time, is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor. In the motor endplate, it causes depolarization, preventing further effects to the normal release of acetylcholine from the presynaptic terminal, and therefore preventing the neural stimulus from affecting the muscle. In the process of binding, decamethonium actually activates (depolarizes) the motor endplate, but since the decamethonium itself is not degraded, the membrane remains depolarized and unresponsive to normal acetylcholine release.

In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥100%

Specifications

동의어
1,10-Decanediaminium, N1,N1,N1,N10,N10,N10-hexamethyl-, bromide (1:2)
사양 및 순도
Moligand™, 10mM in DMSO
생화학 및 생리적 메커니즘
Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.
보관 조건
Store at -80°C
배송
Dry ice packs + Cold packs
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등급
Moligand™
작업 유형
PARTIAL AGONIST
작동 메커니즘
Muscle-type nicotinic acetylcholine receptor partial agonist
이름과 식별자
이성체 SMILES C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C.[Br-].[Br-]
WGK 독일 3
RTECS BP5950000
분자량 418.30
Reaxy-Rn 3728288
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3728288&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

관련 대상(인간)
ACHE Tclin Acetylcholinesterase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
용해성Solubility (25°C) In vitro DMSO: 59 mg/mL (198.82 mM); Ethanol: 2 mg/mL (6.73 mM); Water: Insoluble;
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리뷰

고객 리뷰

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