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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Decamethonium Bromide is a nicotinicAChRpartial agonist andneuromuscularblocking agent.
In vitro
Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. Decamethonium, which has a short action time, is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor. In the motor endplate, it causes depolarization, preventing further effects to the normal release of acetylcholine from the presynaptic terminal, and therefore preventing the neural stimulus from affecting the muscle. In the process of binding, decamethonium actually activates (depolarizes) the motor endplate, but since the decamethonium itself is not degraded, the membrane remains depolarized and unresponsive to normal acetylcholine release.
In vivo
Cell Data
cell lines:
Concentrations:
Incubation Time:
Powder Purity:≥100%
| 이성체 SMILES | C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C.[Br-].[Br-] |
|---|---|
| WGK 독일 | 3 |
| RTECS | BP5950000 |
| 분자량 | 418.30 |
| Reaxy-Rn | 3728288 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3728288&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| 용해성 | Solubility (25°C) In vitro DMSO: 59 mg/mL (198.82 mM); Ethanol: 2 mg/mL (6.73 mM); Water: Insoluble; |
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