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Deoxyelephantopin - ≥99% , CAS No.29307-03-7
주문 가능
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요
Deoxyelephantopin, a natural bioactive sesquiterpene lactone from Elephantopus scaber , has shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB , MAPK , PI3K/Akt , and β-catenin signaling
In Vitro
Deoxyelephantopin inhibits the cell growth of HCT 116 (colorectal), K562 (chronic myeloid leukemia), KB (oral), and T47D (breast) cancer cell lines with IC 50 s of 7.46, 4.02, 3.35, 1.86 μg/mL, respectively. Deoxyelephantopin increases the expression of p53, p-JNK, and p-p38 and decreases the expression of p-STAT3 and p-mTOR in cancer cells. Deoxyelephantopin downregulates MMP-2 and MMP-9, uPA, and uPAR mRNA levels in cancer cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:NF-κB
Specifications
사양 및 순도
≥99%
생화학 및 생리적 메커니즘
Deoxyelephantopin, a natural bioactive sesquiterpene lactone from Elephantopus scaber , has shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB , MAPK , PI3K/Akt , and β-catenin signaling.
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
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작업 유형
INHIBITOR
순수함
≥99%
이름과 식별자
정식 스마일
CC1=CC2C(C(CC3=CC(C1)OC3=O)OC(=O)C(=C)C)C(=C)C(=O)O2
IUPAC Name
(10-methyl-5-methylidene-6,14-dioxo-7,13-dioxatricyclo[10.2.1.04,8]pentadeca-1(15),9-dien-3-yl) 2-methylprop-2-enoate
InChIKey
JMUOPRSXUVOHFE-UHFFFAOYSA-N
INCHI
1S/C19H20O6/c1-9(2)17(20)24-15-8-12-7-13(23-19(12)22)5-10(3)6-14-16(15)11(4)18(21)25-14/h6-7,13-16H,1,4-5,8H2,2-3H3
이성체 SMILES
CC1=CC2C(C(CC3=CC(C1)OC3=O)OC(=O)C(=C)C)C(=C)C(=O)O2
분자량
344.4
Reaxy-Rn
25965389
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25965389&ln=
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
3D 구조
상호 작용 화학 구조 모델
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
| 용해성 | DMSO : 33.33 mg/mL (96.79 mM; Need ultrasonic) |
|---|
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