Dexamethasone Solution (10mM) - BioReagent, for Cell culture, Sterile, 10 mM in DMSO , CAS No.50-02-2

CAS: 50-02-2 Cat. No.: C1524668 분자식: C₂₂H₂₉FO₅ 분자량: 392.46 Beilstein Registry Number: 2066651 EC 번호: 200-003-9

등급 & 순도 BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Synonyms

Dexamethasone Solution | DEX | DXM

Storage

Store at 2-8°C,Do not freeze

Shipped In

Wet ice

개요

Dexamethasone is an adrenocortical hormone substance with multiple pharmacological effects including anti‑inflammatory, anti‑allergic, immunosuppressive and anti‑shock activities. It exerts certain physiological effects on cell culture, cell signal transduction and gene expression. Dexamethasone can induce disorder of hepatic glucose and lipid metabolism; inhibit the activation of the PI3K/Akt pathway and trigger osteoblast apoptosis; elevate intracellular ROS levels and mitochondrial superoxide production. It also induces the differentiation of human mesenchymal stem cells (MSCs), triggers autophagy in B‑cell acute lymphoblastic leukemia (B‑ALL), down‑regulates activated NF‑κB levels in immature dendritic cells (DCs), and suppresses their differentiation into mature DCs.

Dexamethasone Solution is a cell‑culture‑grade 10 mM stock solution. Researchers may dilute it at an appropriate ratio according to experimental requirements prior to direct use.

Product Properties:

CAS NO.: 50‑02‑2

Formula: C₂₂H₂₉FO₅

Molecular weight: 392.461

Appearance: Colorless transparent solution

Solubility: Soluble in ethanol and DMSO, slightly soluble in water

Melting point: 255～264 °C

Structure:

Precautions:

1. For your safety and health, please wear a lab coat and disposable gloves during operation.

2. This reagent is for research use only.

사양

동의어

Dexamethasone Solution | DEX | DXM

사양 및 순도

BioReagent, for Cell culture, Sterile, 10 mM in DMSO

안정성 및 스토리지

Store at 2-8°C long term (24 months). Store in the dark.

보관 조건

Store at 2-8°C,Do not freeze

배송

Wet ice

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등급

BioReagent, 불임, 세포 배양용

Product Line

생물 제품

제품 특성

ALogP

1.9

이름과 식별자

이성체 SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C

WGK 독일

2

RTECS

TU3980000

대체 CAS

23495-06-9,50-02-2

NSC 번호

34521

MeSH 용어

Decaject;Decaject L.A.;Decaject-L.A.;Decameth;Decaspray;Dexamethasone;Dexasone;Dexpak;Hexadecadrol;Hexadrol;Maxidex;Methylfluorprednisolone;Millicorten;Oradexon

분자량

392.46

Beilstein

2066651

Reaxy-Rn

2341697

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2341697&ln=

화학 및 물리적 특성

• 용해성: Soluble in ethanol and DMSO, slightly soluble in water
• 녹는점(°C): 262-264°C