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diABZI-C2-NH2 - ≥96% , CAS No.2137975-93-8
주문 가능
GRADE & PURITY ≥96%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Why this grade
≥96% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요
diABZI-C2-NH2, an active analogue containing a primary amine functionality, is a STING agonist.
In Vitro
The author developed a linking strategy to synergize the effect of two symmetry-related amidobenzimidazole (ABZI)-based compounds to create linked ABZIs (diABZIs) with enhanced binding to STING and cellular function. Intravenous administration of a diABZI STING agonist to immunocompetent mice with established syngeneic colon tumours elicited strong anti-tumour activity, with complete and lasting regression of tumors. diABZI-C2-NH2 is covalently immobilized on sepharose beads and is used to affinity-capture potential target proteins from a THP1 cell lysate. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
사양 및 순도
≥96%
생화학 및 생리적 메커니즘
diABZI-C2-NH2, an active analogue containing a primary amine functionality, is a STING agonist.
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
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순수함
≥96%
이름과 식별자
정식 스마일
O=C(C1=CC=C2C(N=C(NC(C3=CC(C)=NN3CC)=O)N2CCCCN4C5=CC=C(C(N)=O)C=C5N=C4NC(C6=CC(C)=NN6CC)=O)=C1)NCCN
분자량
721.81
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
| 용해성 | DMSO : 100 mg/mL (138.54 mM; Need ultrasonic) |
|---|
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리뷰
고객 리뷰
자주 묻는 질문
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
What is the purity of this product?
This product is supplied at ≥96% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2137975-93-8, the molecular formula is C36H43N13O4, and the molecular weight is 721.81 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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