Dihydroethidium - 10mM in DMSO , CAS No.104821-25-2

CAS: 104821-25-2 Cat. No.: D420461 분자식: C₂₁H₂₁N₃ 분자량: 315.41 Beilstein Registry Number: 5107482

GRADE & PURITY 10mM in DMSO

Synonyms

Hydroethidine | J-100119 | AKOS015915966 | FT-0624954 | PH011085 | Hydroethidine;PD-MY 003 | Dihydroethidium - CAS 38483-26-0 | Enoxacinum (Latin) | NSC-408120 | 5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine | Q3027884 | BCP15712 | SCHEMBL79004 | 5-ethyl

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Hydroethidine operates effectively as a probe for measurement of reactive oxygen species. The dye enters cells freely and is dehydrogenated to ethidium bromide. The probe has been used extensively with NK cell and as a vital dye for identification of proliferation and hypoxic cells in tumors. Studies have been performed using neutrophils and endothelial cells as well as HL60 cells and macrophages. A major advantage of this probe is its ability to distinguish between superoxide and H2O2. Fluorescence emission occurs at around 600 nm.
Redox indicator. Blue fluorescence until oxidized to ethidium

Specifications

동의어

Hydroethidine | J-100119 | AKOS015915966 | FT-0624954 | PH011085 | Hydroethidine;PD-MY 003 | Dihydroethidium - CAS 38483-26-0 | Enoxacinum (Latin) | NSC-408120 | 5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine | Q3027884 | BCP15712 | SCHEMBL79004 | 5-ethyl

사양 및 순도

10mM in DMSO

보관 조건

Protected from light,Store at -80°C

배송

Dry ice packs + Cold packs

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이름과 식별자

Pubchem Sid

528769626

정식 스마일

CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4

IUPAC Name

5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine

InChIKey

XYJODUBPWNZLML-UHFFFAOYSA-N

INCHI

1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3

이성체 SMILES

CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4

WGK 독일

3

분자량

315.41

Beilstein

5107482

Reaxy-Rn

5107482

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5107482&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 분류 Quinolines and derivatives
      • Subclass Phenylquinolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 분류: Quinolines and derivatives
• Subclass: Phenylquinolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylquinolines
• Alternative Parents: Phenanthridines and derivatives Aminoquinolines and derivatives Dialkylarylamines Aralkylamines Benzene and substituted derivatives Azacyclic compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Phenylquinoline - Benzoquinoline - Phenanthridine - Aminoquinoline - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aralkylamine - Benzenoid - Monocyclic benzene moiety - Tertiary amine - Azacycle - Amine - Primary amine - Hydrocarbon derivative - Organonitrogen compound - Organopnictogen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
• 설명: This compound belongs to the class of organic compounds known as phenylquinolines. These are heterocyclic compounds containing a quinoline moiety substituted with a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

화학 및 물리적 특성

• 감도: Air sensitive.Light sensitive.
• 분자량: 315.400 g/mol
• XLogP3: 3.900
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 315.174 Da
• Monoisotopic Mass: 315.174 Da
• Topological Polar Surface Area: 55.300 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 419.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1