DLinDMA - ≥98% , CAS No.871258-12-7

CAS: 871258-12-7 Cat. No.: D413024 분자식: C₄₁H₇₇NO₂ 분자량: 616.16

GRADE & PURITY ≥98%

Synonyms

1-Propanamine, N,N-dimethyl-2,3-bis((9Z,12Z)-9,12-octadecadien-1-yloxy)- | NFQBIAXADRDUGK-KWXKLSQISA-N | 1,2-dilinoleyloxy-n,n-dimethyl-3-aminopropane | N,N-dimethyl-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoxy]propan-1-amine | 1,2-dilinoleyloxy-3-dimethylamino

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

개요

Information

DLinDMA is an ionizable cationic lipid for siRNA delivery. DLinDMA is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark.

Specifications

동의어

1-Propanamine, N,N-dimethyl-2,3-bis((9Z,12Z)-9,12-octadecadien-1-yloxy)- | NFQBIAXADRDUGK-KWXKLSQISA-N | 1,2-dilinoleyloxy-n,n-dimethyl-3-aminopropane | N,N-dimethyl-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoxy]propan-1-amine | 1,2-dilinoleyloxy-3-dimethylamino

사양 및 순도

≥98%

생화학 및 생리적 메커니즘

DLinDMA is an ionizable cationic lipid for siRNA delivery. DLinDMA is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥98%

이름과 식별자

• Pubchem Sid: 528771844
• 정식 스마일: CCCCCC=CCC=CCCCCCCCCOCC(CN(C)C)OCCCCCCCCC=CCC=CCCCCC
• IUPAC Name: N,N-dimethyl-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoxy]propan-1-amine
• InChIKey: NFQBIAXADRDUGK-KWXKLSQISA-N
• INCHI: 1S/C41H77NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h13-16,19-22,41H,5-12,17-18,23-40H2,1-4H3/b15-13-,16-14-,21-19-,22-20-
• 이성체 SMILES: CCCCC/C=C\C/C=C\CCCCCCCCOCC(CN(C)C)OCCCCCCCC/C=C\C/C=C\CCCCC
• 분자량: 616.16
• Reaxy-Rn: 29349580
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29349580&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • 분류 Organonitrogen compounds
      • Subclass Amines
        • Level5 Tertiary amines
          • Level6 Trialkylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• 분류: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Tertiary amines
• Direct Parent: Trialkylamines
• Alternative Parents: Dialkyl ethers Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Tertiary aliphatic amine - Ether - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aliphatic acyclic compound
• 설명: This compound belongs to the class of organic compounds known as trialkylamines. These are organic compounds containing a trialkylamine group, characterized by exactly three alkyl groups bonded to the amino nitrogen.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

화학 및 물리적 특성

• 분자량: 616.100 g/mol
• XLogP3: 14.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 35
• Exact Mass: 615.595 Da
• Monoisotopic Mass: 615.595 Da
• Topological Polar Surface Area: 21.700 Ų
• Heavy Atom Count: 44
• Formal Charge: 0
• Complexity: 651.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1