DPP-IV-IN-1 - ≥98% , CAS No.625110-37-4

CAS: 625110-37-4 Cat. No.: D646861 분자식: C₁₁H₁₈FN₃O₂ 분자량: 243.28

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) , a highly specific serine protease , with an IC 50 of 4.6 nM.

In Vivo

DPP-IV-IN-1 (0.1 and 0.3 mg/kg, p.o.) reduces the increase in plasma glucose beginning 30 min after glucose loading, and significantly suppresses hyperglycemia at the dose of 0.3 mg/kg in a rat model of obesity and impaired glucose tolerance. The effect is based on its inhibitory effect on plasma DPP-IV activity . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

사양 및 순도

≥98%

생화학 및 생리적 메커니즘

DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) , a highly specific serine protease , with an IC 50 of 4.6 nM.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

INHIBITOR

순수함

≥98%

이름과 식별자

• 분자량: 243.28

화학 및 물리적 특성

• 용해성: DMSO : 125 mg/mL (513.81 mM; Need ultrasonic)