Determine the necessary mass, volume, or concentration for preparing a solution.
DRB18 - ≥98% , CAS No.D414435
주문 가능
등급 & 순도 ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
이 등급을 선택하는 이유
≥98% 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.
보관 및 배송
Store at -20°C Ice chest + Ice pads 출고. 정확한 사양은 로트별 COA를 확인하세요.
품질 문서
SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.
문헌적 근거
크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.
개요
Information
DRB18 DRB18 is a pan-GLUT (glucose transporters) inhibitor that inhibits growth and proliferation in several different cancer types with IC50 high nM range.
Targets
GLUT
In vitro
DRB18 inhibits growth and proliferation in about 90% of the 60 different cancer cell lines in 9 major cancer types. DRB18 treatment leads to significant changes in glucose-based metabolism in A549 lung cancer cells, including cell death via ER/oxidative stress and necrosis.
In vivo
DRB18 (10 mg/kg) treatment thrice a week significantly reduces growth in Xenograft A549 tumors.
사양
사양 및 순도
≥98%
생화학 및 생리적 메커니즘
DRB18 is a pan-GLUT (glucose transporters) inhibitor that inhibits growth and proliferation in several different cancer types with IC50 high nM range.
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
순수함
≥98%
제품 특성
ALogP
5.767
HBD 수
4
회전 가능한 결합
6
이름과 식별자
정식 스마일
CC1=CC=C(CNC2=C(NCC3=CC(=C(C)C=C3)O)C=C(Cl)C=C2)C=C1O
분자량
382.88
Reaxy-Rn
36374407
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36374407&ln=
문서
📋 안전 데이터 시트(SDS)
위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.
<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3고급 데이터
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
| 용해성 | Solubility (25°C) In vitro DMSO: 76 mg/mL (198.49 mM); Ethanol: 76 mg/mL (198.49 mM); Water: Insoluble; |
|---|---|
| DMSO(mg/mL) 최대 용해도 | 76 |
| DMSO(mM) 최대 용해도 | 198.495612202257 |
| 물(mg/mL) 최대 용해도 | ＜1 |
솔루션 계산기
리뷰
고객 리뷰
자주 묻는 질문
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is D414435, the molecular formula is C22H23ClN2O2, and the molecular weight is 382.88 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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