10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC 50 of 0.28 μM for USP8
In Vitro
DUBs-IN-2 (compound 22 e) is a potent USP8 inhibitor with an IC 50 of 0.28 μM, and has no effect on USP7, with an IC 50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC 50 values of 0.5-1.5 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:IC50: 0.28 μM (USP8)
Specifications
사양 및 순도
10mM in DMSO
생화학 및 생리적 메커니즘
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC 50 of 0.28 μM for USP8.
보관 조건
Store at -80°C
배송
Dry ice packs + Cold packs
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
작업 유형
INHIBITOR
이름과 식별자
분자량
275.26
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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