Dyclonine HCl - 10mM in DMSO , Sodium channel alpha subunit blocker, CAS No.536-43-6, Sodium channel alpha subunit blocker

CAS: 536-43-6 Cat. No.: D409239 분자식: C₁₈H₂₇NO₂ · HCl 분자량: 325.87 EC 번호: 208-633-6

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

1-​(4-​butoxyphenyl)​-​3-​(1-​piperidinyl)​-1-​propanone,hydrochloride (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Dyclonine HCl Dyclonine HCl is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading t
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

동의어

1-​(4-​butoxyphenyl)​-​3-​(1-​piperidinyl)​-1-​propanone,hydrochloride (1:1)

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Dyclonine HCl is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane\'s permeability to sodium ions, leading to an increased

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

등급

Moligand™

작업 유형

BLOCKER

작동 메커니즘

Sodium channel alpha subunit blocker

이름과 식별자

• 이성체 SMILES: CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl
• WGK 독일: 3
• RTECS: UG8750000
• 분자량: 325.87
• Reaxy-Rn: 3744808
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3744808&ln=

화학 및 물리적 특성

• 녹는점(°C): 175-176°C

참고 문헌

1. Xiaokang Guan, Qiao Lu, Xiangxu Zhao, Xiaowen Yan, Renato Zenobi.  (2023)  Spatio-Temporal Analysis of Anesthetics in Mice by Solid-Phase Microextraction: Dielectric Barrier Discharge Ionization Mass Spectrometry.  ANALYTICAL CHEMISTRY,      [PMID:37560898] [10.1021/acs.analchem.3c02123]

2. Wen-Jing Li, Li-Ying Wen, Yu-Sang Li, He-Bin Tang.  (2026)  Topical Application of Frankincense Oil Extract Potently Ameliorates Psoriasis-like Dermatitis in Mice via Anti-Inflammatory and Skin Barrier-Protective Effects.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  27  (6):   [PMID:41898492] [10.3390/ijms27062629]