Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
이 등급을 선택하는 이유
Moligand™, ≥98% Moligand™ 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.
보관 및 배송
Store at -20°C Ice chest + Ice pads 출고. 정확한 사양은 로트별 COA를 확인하세요.
품질 문서
SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.
문헌적 근거
크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 2편에서 인용되었습니다.
개요
Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.
사양
동의어
STA-4783
사양 및 순도
Moligand™, ≥98%
생화학 및 생리적 메커니즘
Elesclomol significantly induces the expression of heat shock stress response genes and metallothionein genes, a signature transcription profile indicative of oxidative stress in Hs294T cells。Elesclomol significantly inhibits the cell viability of SK-MEL-
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
등급
Moligand™
작업 유형
ACTIVATOR
순수함
≥98%
이름과 식별자
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/528769923
정식 스마일
CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
IUPAC Name
1-N',3-N'-bis(benzenecarbonothioyl)-1-N',3-N'-dimethylpropanedihydrazide
InChIKey
BKJIXTWSNXCKJH-UHFFFAOYSA-N
INCHI
1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25)
이성체 SMILES
CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2
분자량
400.52
Reaxy-Rn
11332608
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11332608&ln=
문서
📋 안전 데이터 시트(SDS)
위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.
<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3고급 데이터
Taxonomic Classification
Taxonomy Tree
- Kingdom Organic compounds
- Superclass Benzenoids
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| 분류 | Benzene and substituted derivatives |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Benzene and substituted derivatives |
| Alternative Parents | 1,3-dicarbonyl compounds Thioamides Carboxylic acid hydrazides Thiocarbonyl compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Monocyclic benzene moiety - 1,3-dicarbonyl compound - Thioamide - Carboxylic acid hydrazide - Carboxylic acid derivative - Hydrocarbon derivative - Organopnictogen compound - Thiocarbonyl group - Organic oxygen compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Carbonyl group - Organic nitrogen compound - Organic oxide - Aromatic homomonocyclic compound |
| 설명 | This compound belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene. |
| External Descriptors | carbohydrazide - thiocarbonyl compound |
3D 구조
상호 작용 화학 구조 모델
관련 대상(인간)
5637 (630 Activities)
A 172 (535 Activities)
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|---|
A204 (242 Activities)
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|---|
A2058 (690 Activities)
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|---|
A-375 (9258 Activities)
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|---|
A-427 (643 Activities)
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|---|
A498 (42825 Activities)
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|---|
A673 (619 Activities)
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|---|
ACHN (49357 Activities)
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|---|
AGS (1999 Activities)
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|---|
BT-20 (503 Activities)
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|---|
BT-474 (2113 Activities)
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|---|
BXPC-3 (2997 Activities)
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|---|
C8166 (1658 Activities)
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|---|
CAKI-1 (44928 Activities)
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|---|
Calu-3 (339 Activities)
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|---|
Calu-6 (398 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CAPAN-1 (772 Activities)
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|---|
CCRF-CEM (65223 Activities)
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|---|
CFPAC-1 (421 Activities)
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|---|
COLO 205 (50209 Activities)
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|---|
COR-L23 (253 Activities)
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|---|
Daoy (570 Activities)
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|---|
DMS-79 (150 Activities)
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|---|
DMS-273 (14108 Activities)
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|---|
DU-145 (51482 Activities)
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|---|
G-361 (890 Activities)
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|---|
G-401 (156 Activities)
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|---|
HL-60 (67320 Activities)
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|---|
HT-1080 (3966 Activities)
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|---|
HT-29 (80576 Activities)
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|---|
HuCCT-1 (128 Activities)
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|---|
Huh-7 (12904 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HuTu80 (255 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
J82 (505 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
JAR (316 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
K562 (73714 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KM12 (47707 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
LoVo (4724 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
M14 (47487 Activities)
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|---|
MCF7 (126967 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MDA-MB-361 (612 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MDA-MB-453 (1139 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MG-63 (795 Activities)
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|---|
NCI-H1975 (4994 Activities)
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MKN-1 (175 Activities)
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|---|
MKN-28 (466 Activities)
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|---|
MKN-45 (2102 Activities)
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|---|
MKN-7 (272 Activities)
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|---|
ML-2 (146 Activities)
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|---|
관련 대상(비인간)
Hdac6 Histone deacetylase 6 (222 Activities)
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|---|
Mycobacterium tuberculosis (203094 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Canis familiaris (36305 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mus musculus (284745 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Rattus norvegicus (775804 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
H4 (48 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
 F2611344 | Certificate of Analysis | May 30, 2026 | E126032 |
| F2611345 | Certificate of Analysis | May 30, 2026 | E126032 |
| F2611346 | Certificate of Analysis | May 30, 2026 | E126032 |
| F2611347 | Certificate of Analysis | May 30, 2026 | E126032 |
| F2611349 | Certificate of Analysis | May 30, 2026 | E126032 |
| L2017180 | Certificate of Analysis | Apr 15, 2026 | E126032 |
| H1624055 | Certificate of Analysis | Nov 06, 2025 | E126032 |
| K2301079 | Certificate of Analysis | Aug 11, 2025 | E126032 |
| A2510120 | Certificate of Analysis | Jan 14, 2025 | E126032 |
화학 및 물리적 특성
| 용해성 | DMSO ≥78mg/mL Water <1.2mg/mL Ethanol <1.2mg/mL |
|---|---|
| 분자량 | 400.500 g/mol |
| XLogP3 | 2.900 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 400.103 Da |
| Monoisotopic Mass | 400.103 Da |
| Topological Polar Surface Area | 129.000 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 510.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
자주 묻는 질문과 기사
Citations of This Product
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