≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
EN6 is a novel covalentautophagyactivator and targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase with an IC50 of 1.7 μM for recombinant human ATP6V1A protein.
| ALogP | 3.07 |
|---|---|
| hba_count | 3 |
| HBD 수 | 2 |
| 회전 가능한 결합 | 5 |
| Pubchem Sid | 504772744 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772744 |
| 정식 스마일 | C=CC(=O)NC1=C(C=CC(=C1)NC(=O)C2=CN(N=C2)C3=CC=CC=C3F)F |
| IUPAC Name | 1-(2-fluorophenyl)-N-[4-fluoro-3-(prop-2-enoylamino)phenyl]pyrazole-4-carboxamide |
| InChIKey | SUSXQEYPNDORDQ-UHFFFAOYSA-N |
| INCHI | 1S/C19H14F2N4O2/c1-2-18(26)24-16-9-13(7-8-14(16)20)23-19(27)12-10-22-25(11-12)17-6-4-3-5-15(17)21/h2-11H,1H2,(H,23,27)(H,24,26) |
| 이성체 SMILES | C=CC(=O)NC1=C(C=CC(=C1)NC(=O)C2=CN(N=C2)C3=CC=CC=C3F)F |
| 분자량 | 368.34 |
| Reaxy-Rn | 36433117 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36433117&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| 분류 | Benzene and substituted derivatives |
| Subclass | Anilides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Aromatic anilides |
| Alternative Parents | Phenylpyrazoles Pyrazole-4-carboxamides N-arylamides Fluorobenzenes Aryl fluorides Vinylogous amides Heteroaromatic compounds Acrylic acids and derivatives Secondary carboxylic acid amides Azacyclic compounds Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Aromatic anilide - Phenylpyrazole - Pyrazole-4-carboxamide - N-arylamide - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Azole - Acrylic acid or derivatives - Pyrazole - Heteroaromatic compound - Vinylogous amide - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic oxide - Organic nitrogen compound - Carbonyl group - Aromatic heteromonocyclic compound |
| 설명 | This compound belongs to the class of organic compounds known as aromatic anilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with an aromatic group. They have the general structure RNC(=O)R', where R= benzene, and R = aryl group. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
 K2219571 | Certificate of Analysis | Sep 13, 2022 | E413569 |
| K2219597 | Certificate of Analysis | Sep 13, 2022 | E413569 |
| K2219598 | Certificate of Analysis | Sep 13, 2022 | E413569 |
| K2219651 | Certificate of Analysis | Sep 13, 2022 | E413569 |
| DMSO(mg/mL) 최대 용해도 | 74 |
|---|---|
| DMSO(mM) 최대 용해도 | 200.901341152196 |
| 물(mg/mL) 최대 용해도 | ＜1 |
| 분자량 | 368.300 g/mol |
| XLogP3 | 2.700 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 5 |
| Exact Mass | 368.108 Da |
| Monoisotopic Mass | 368.108 Da |
| Topological Polar Surface Area | 76.000 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 562.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Enke Feng, Guangchao Zheng, Xue Li, Mengzhen Zhang, Xiaoqin Li, Xinning Han, Linan Cao, Zhiqiang Wu. (2022) A toughened, transparent, anti-freezing and solvent-resistant hydrogel towards environmentally tolerant strain sensor and soft connection. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2022.130390] |
| 2. Tianjiao Zhang, Haipeng Jiang, Sheng Shang, Kai Zhang, Wei Gao. (2021) Synthesis of aluminum hydroxide/Zinc borate composite inhibitor and its inhibition effect on aluminum dust explosion. CHEMICAL ENGINEERING SCIENCE, [PMID:] [10.1016/j.ces.2021.117204] |
| 3. Wang Guo-hui, He Man-li, Chai Fan-chao, Feng Jun-dong, Dai Yao-dong. (2019) Enhancement of flame retardancy and radiation shielding properties of ethylene vinyl acetate based radiation shielding composites by EB irradiation. PROGRESS IN NUCLEAR ENERGY, [PMID:] [10.1016/j.pnucene.2019.01.001] |
| 4. Yi Qian, Shaojie Zhou, Xilei Chen. (2016) Flammability and thermal degradation behavior of ethylene-vinyl acetate/layered double hydroxides/zinc borate composites. POLYMERS FOR ADVANCED TECHNOLOGIES, 28 (3): (353-361). [PMID:] [10.1002/pat.3895] |
| 5. Shuqi Zhang, Jiangping Zhao, Yong Yang, YaChao Wang, Kainan Yu. (2025) Suppression effect and mechanism of melamine polyphosphate /zinc borate composite suppressant on aluminum dust explosion. POWDER TECHNOLOGY, [PMID:] [10.1016/j.powtec.2025.120777] |
| 6. Guo-hui Wang, Man-li He, Dan-feng Jiang, Fan He, Shu-quan Chang, Yao-dong Dai. (2017) The properties of neutron shielding and flame retardant of EVA polymer after modified by EB accelerator. RADIATION PHYSICS AND CHEMISTRY, [PMID:] [10.1016/j.radphyschem.2017.03.038] |
