Enoxolone - Moligand™, 10mM in DMSO , Inhibitor of hydroxysteroid 11-beta dehydrogenase 1;Inhibitor of hydroxysteroid 11-beta dehydrogenase 2, CAS No.471-53-4, Inhibitor of hydroxysteroid 11-beta dehydrogenase 1;Inhibitor of hydroxysteroid 11-beta dehydrogenase 2

CAS: 471-53-4 Cat. No.: E407903 분자식: C₃₀H₄₆O₄ 분자량: 470.68 Beilstein Registry Number: 2229654 EC 번호: 207-444-6

등급 & 순도 Moligand™, 10mM in DMSO

Synonyms

Glycyrrhetin | Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Enoxolone Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥95%

사양

동의어

Glycyrrhetin | Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)-

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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등급

Moligand™

작업 유형

INHIBITOR

작동 메커니즘

Inhibitor of hydroxysteroid 11-beta dehydrogenase 1;Inhibitor of hydroxysteroid 11-beta dehydrogenase 2

이름과 식별자

이성체 SMILES

C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O

WGK 독일

3

RTECS

RK0180000

분자량

470.68

Beilstein

2229654

Reaxy-Rn

3041142

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3041142&ln=

관련 대상(인간)

HSD11B2 Tchem Corticosteroid 11-beta-dehydrogenase isozyme 2 (0 Activities)

Discover Target: HSD11B2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSD11B1 Tclin Corticosteroid 11-beta-dehydrogenase isozyme 1 (0 Activities)

Discover Target: HSD11B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)

Discover Target: SLCO1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)

Discover Target: SLCO1B3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

화학 및 물리적 특성

• 특정 회전[α]: 162 ° (C=1, MeOH)
• 녹는점(°C): 292-295°C