Epiandrosterone - 10mM in DMSO , CAS No.481-29-8

CAS: 481-29-8 Cat. No.: E407759 분자식: C₁₉H₃₀O₂ 분자량: 290.4 EC 번호: 207-563-3

등급 & 순도 10mM in DMSO

Synonyms

3β-androsterone, EpiA | 3β-Hydroxy-5α-androstane-17-one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Epiandrosterone Epiandrosterone (3β-androsterone, EpiA) is a steroid hormone with weak androgenic activity, is a natural metabolite of DHEA.
In vitro

Epiandrosterone is a natural metabolite of dehydroepiandrosterone (DHEA) via the 5α-reductaseenzyme. Epiandrosterone is formed in peripheral tissues, from which it is released into the circulation and is ultimately excreted in the urine. Epiandrosterone is only a weak androgen, but it is widely recognized to inhibit the pentosephosphate pathway (PPP) and to decrease intracellular NADPH levels. Epiandrosterone attenuates NO-evoked relaxation of pulmonary artery , although it inhibits angiotensin II- and hypoxia-induced vasoconstriction in isolated lungs and relaxes isolated pulmonary arteries pre-constricted with KCl.

In vivo

Cell Data

cell lines：MES-SA, MDA-MB-468, MCF-7, HCT116, HT29, U87MG, PC-3 and DU145 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

사양

동의어

3β-androsterone, EpiA | 3β-Hydroxy-5α-androstane-17-one

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

Epiandrosterone (3β-androsterone, EpiA) is a steroid hormone with weak androgenic activity, is a natural metabolite of DHEA.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

AGONIST

이름과 식별자

이성체 SMILES

C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O

분자량

290.4

Reaxy-Rn

2055720

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2055720&ln=