ExactAb™, Validated, 1mg/mL ExactAb™,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Mouse anti Human ErbB 2 Antibody, Monoclonal(1C4-1H3-1H3), could be used for WB, IHC and so on .
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function
Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
In the nucleus is involved in transcriptional regulation. Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. Implicated in transcriptional activation of CDKN1A; the function involves STAT3 and SRC. Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.
ErbB2Her2 Mouse mAb (Ab102061) - Western Blot
All lanes: ErbB2Her2 Mouse mAb (Ab102061) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/50000 dilution
Predicted band size: 185 kDa
Observed band size: 181 kDa
Exposure time: 10.0 s
ErbB2Her2 Mouse mAb (Ab102061) - IHC
Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using ErbB2Her2 Mouse mAb (Ab102061). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
| 적용 | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50 - 1/100 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
 ZJ24F0911293 | Certificate of Analysis | Jul 09, 2026 | Ab102061 |
| ZJ23F0800859 | Certificate of Analysis | Aug 22, 2023 | Ab102061 |
| ZJ23F0800858 | Certificate of Analysis | Aug 22, 2023 | Ab102061 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Validated grade guide → View ExactAb™ grade guide →
