Recombinant Human FAM107A Protein: Key FAQs

Recombinant Human FAM107A Protein is a research-grade recombinant protein produced for scientific investigation of the FAM107A gene product, a member of the DRR1/FAM107 family implicated in stress response, neurological function, and tumor suppression.

Product Name

Recombinant Human FAM107A Protein

SKU

rp371471

Protein Family

FAM107 / DRR1 family

Species Origin

Human (Homo sapiens)

Application

Research use only (RUO)

Supplier Reference

absea#PP-5624

What Is FAM107A and Why Is It Scientifically Relevant?

FAM107A (Family with Sequence Similarity 107, Member A), also known as DRR1 (Down-Regulated in Renal Cell Carcinoma 1), is a small cytosolic protein encoded by the FAM107A gene in humans. It belongs to the FAM107/DRR protein family and has been studied in the context of tumor suppression, cellular stress responses, and neurological development.

FAM107A expression has been reported to be down-regulated in several cancer types, including renal cell carcinoma, suggesting a role as a tumor suppressor. Additionally, studies have indicated that FAM107A may play a role in actin cytoskeleton organization and neuronal function, making it of interest in both oncology and neuroscience research.

Recombinant Human FAM107A Protein enables researchers to perform in vitro biochemical assays, protein–protein interaction studies, and functional characterization without relying on endogenous protein sources.

What Are the Recommended Applications for This Protein?

Recombinant Human FAM107A Protein (rp371471) is intended for research use only and is suitable for a range of in vitro applications, including:

• Biochemical assays: Enzyme-linked immunosorbent assays (ELISA) and similar plate-based assays to study protein expression or binding interactions.
• Protein–protein interaction studies: Pull-down assays and co-immunoprecipitation experiments to identify FAM107A binding partners.
• Western blot standards: Use as a positive control or molecular weight marker for FAM107A detection in experimental samples.
• Antibody validation: Serve as an antigen to validate anti-FAM107A antibodies for specificity and sensitivity.
• Cell-based functional studies: Exogenous addition to cell culture systems to investigate FAM107A's effects on cell viability, morphology, or signaling pathways.

This product is not intended for diagnostic, therapeutic, or clinical use.

How Should Recombinant Human FAM107A Protein Be Stored and Handled?

Proper storage and handling are critical to maintaining the activity and integrity of recombinant proteins. Although specific storage conditions for rp371471 should be confirmed in the product datasheet, the following general best practices apply to recombinant proteins of this class:

• Short-term storage (up to 1 month): Store at 4 °C in the supplied buffer.
• Long-term storage: Aliquot to avoid repeated freeze-thaw cycles and store at −20 °C or −80 °C as recommended on the product datasheet.
• Avoid repeated freeze-thaw cycles: Each cycle can result in protein aggregation and loss of activity.
• Carrier protein addition: If the protein is at low concentration, consider adding a carrier protein such as 0.1% BSA to prevent adsorption to tube surfaces.
• Sterile handling: Use sterile technique when preparing aliquots to prevent microbial contamination.

Always refer to the official product datasheet for lot-specific storage instructions.

Quality, Purity, and Formulation Considerations

Recombinant proteins supplied for research use are typically characterized for purity, identity, and biological activity. For Recombinant Human FAM107A Protein (rp371471), researchers should consult the current product datasheet (referenced as absea#PP-5624) for lot-specific quality control data, which may include:

• Purity assessment: SDS-PAGE or HPLC analysis to confirm protein purity (commonly ≥85–95% for research-grade recombinant proteins, though the exact specification should be confirmed on the datasheet).
• Identity confirmation: Mass spectrometry or N-terminal sequencing to confirm the correct protein sequence.
• Endotoxin level: Endotoxin content is particularly important for cell-based assays; confirm the level meets your experimental requirements.
• Formulation: The protein is typically supplied in a defined buffer; exact composition should be verified on the datasheet to ensure compatibility with your assay conditions.

Contact Aladdin Scientific technical support if additional quality documentation (e.g., CoA, SDS) is required for your records or institutional compliance.

Ordering, Shipping, and Technical Support

Recombinant Human FAM107A Protein is available from Aladdin Scientific under SKU rp371471. The following information is relevant for procurement and logistics:

• Ordering: Place orders through the Aladdin Scientific website or by contacting your regional sales representative. Reference SKU rp371471 to ensure accurate fulfillment.
• Shipping: Recombinant proteins are typically shipped on dry ice to maintain cold chain integrity. Confirm shipping conditions with Aladdin Scientific at the time of order, especially for international shipments.
• Upon receipt: Inspect the package immediately. If the dry ice has sublimated or the product appears compromised, contact Aladdin Scientific customer service before use.
• Technical support: For application-specific questions, protocol optimization, or troubleshooting, reach out to Aladdin Scientific's technical support team. Reference the product SKU and lot number when submitting inquiries.
• Returns and refunds: Consult Aladdin Scientific's returns and refund policy for reagent products; conditions may apply based on storage requirements and handling history.

Frequently asked questions

What is Recombinant Human FAM107A Protein used for in research?

Recombinant Human FAM107A Protein (rp371471) is used for in vitro biochemical assays, protein–protein interaction studies, antibody validation, and as a positive control in Western blot experiments. It is also suitable for investigating FAM107A's roles in tumor suppression and neurological function in cell-based models. This product is for research use only.

How should I store Recombinant Human FAM107A Protein to preserve its activity?

For short-term use, store the protein at 4 °C. For long-term storage, aliquot the protein and store at −20 °C or −80 °C as specified in the product datasheet to avoid repeated freeze-thaw cycles, which can cause aggregation and loss of activity. Always refer to the lot-specific datasheet (absea#PP-5624) for definitive storage instructions.

What is the purity of Recombinant Human FAM107A Protein (rp371471)?

The exact purity specification for rp371471 should be confirmed on the current product datasheet or Certificate of Analysis (CoA), as values may vary by lot. Research-grade recombinant proteins are typically characterized by SDS-PAGE or HPLC. Please contact Aladdin Scientific to request the CoA for your specific lot.

Is Recombinant Human FAM107A Protein suitable for cell-based assays?

Recombinant Human FAM107A Protein can be used in cell-based functional studies; however, researchers should verify the endotoxin level reported on the product datasheet before use in cell culture, as endotoxin contamination can confound results. Contact Aladdin Scientific technical support for guidance on optimal concentrations and assay formats.

How do I order Recombinant Human FAM107A Protein from Aladdin Scientific?

You can order Recombinant Human FAM107A Protein by referencing SKU rp371471 on the Aladdin Scientific website or by contacting your regional sales representative. For bulk quantities or custom requirements, please reach out to Aladdin Scientific's sales team directly for pricing and availability.

References

1. Aladdin Scientific product page for Recombinant Human FAM107A Protein (rp371471); supplier reference absea#PP-5624.
2. General literature on FAM107A / DRR1 as a tumor suppressor and its role in renal cell carcinoma and neurological function — specific citations to be added upon literature review.

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.