Non-Steroidal Anti-Inflammatory Drugs
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to alleviate pain, inflammation, swelling, and fever through inhibition of cyclooxygenase enzymes COX-1 and COX-2.
Topic
Anti-cancer
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
8 resources · protocols, FAQs & articles
Rapamycin
Rapamycin is an immunosuppressive agent widely used to prevent transplant rejection in organ recipients. Its primary mechanism of action involves inhibition of mTOR signaling through complex formation with FK-binding protein 12 (FKBP12), which prevents mTOR activation. As a result, ...
9-cis-Retinoic Acid
9-cis Retinoic Acid is a biologically active form of vitamin A and serves as an endogenous ligand for retinoid X receptors (RXRs). Like other retinoids, it also activates retinoic acid receptors (RARs). Retinoids are critical regulators of numerous cellular processes, including cell ...
Resveratrol
Phytoalexins are naturally occurring secondary metabolites synthesized by plants in response to environmental stressors such as fungal infection, heavy metal exposure, or ultraviolet (UV) radiation.
Statins Antihyperlipidemics Anticancer Agents
Statins are a class of compounds widely used for their antihyperlipidemic activity, clinically prescribed to lower plasma levels of low-density lipoprotein (LDL) and total cholesterol. Their primary mechanism of action is the inhibition of HMG-CoA reductase, a key enzyme in cholesterol ...
Isothiocyanates
Watercress (Nasturtium officinale), a cruciferous vegetable, is rich in isothiocyanate compounds. These compounds exhibit anticancer properties and can induce Phase II detoxifying enzyme activity. The primary bioactive component of watercress is phenethyl isothiocyanate (PEITC), followed by ...
Resveratrol
Resveratrol is a stilbene-type phytoalexin found in the skins and seeds of grapes, as well as in various other plants such as peanuts, soybeans, and mulberries. Similar to other phytoalexins, resveratrol exhibits diverse bioactivities, including antioxidant, anticancer, neuroprotective, and ...
Fluid chemistry: Lighting the fire of hope for the large-scale production of anticancer drugs
A paper published August 24 at Org. Process Res. Dev by Professor Sean M. Kell et al. describes a robust and efficient continuous flow process technique for the synthesis of quinazoline organozinc reagents for KRAS G12C inhibitor divarasib.
Related topics
Techniques often explored alongside immunological experiments.