Articles by tag "skeletal muscle"

1. ActRIIA/ActRIIB in Weight Loss: Muscle Preservation and Adipose Regulation
   posted this at 2026. 10. 15.

   3
   ActRIIA and ActRIIB are important receptors for TGF-β superfamily ligands such as Myostatin/GDF8 and Activin A. Through SMAD2/3 signaling, they restrict skeletal muscle growth and participate in adipose tissue metabolism. Blocking ActRIIA/ActRIIB can increase or preserve Lean Mass while ...