Ganoderol B - ≥97% , CAS No.104700-96-1

CAS: 104700-96-1 Cat. No.: G648783 분자식: C₃₀H₄₈O₂ 분자량: 440.70 PubChem CID: 13934286

GRADE & PURITY ≥97%

Synonyms

(3beta,24E)-Lanosta-7,9(11),24-trien-3,26-diol | HY-N2223 | UNII-Z99BBB5WR6 | (+)-Ganoderol B | (3S,5R,10S,13R,14R,17R)-17-((E,2R)-7-HYDROXY-6-METHYLHEPT-5-EN-2-YL)-4,4,10,13,14-PENTAMETHYL-2,3,5,6,12,15,16,17-OCTAHYDRO-1H-CYCLOPENTA(A)PHENANTHREN-3-OL |

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Ganoderol B is a potent α-glucosidase inhibitor. Ganoderol B has high α-glucosidase inhibition with an IC 50 of 48.5 μg/mL (119.8 μM).

Form:Solid

Specifications

동의어

(3beta,24E)-Lanosta-7,9(11),24-trien-3,26-diol | HY-N2223 | UNII-Z99BBB5WR6 | (+)-Ganoderol B | (3S,5R,10S,13R,14R,17R)-17-((E,2R)-7-HYDROXY-6-METHYLHEPT-5-EN-2-YL)-4,4,10,13,14-PENTAMETHYL-2,3,5,6,12,15,16,17-OCTAHYDRO-1H-CYCLOPENTA(A)PHENANTHREN-3-OL |

사양 및 순도

≥97%

생화학 및 생리적 메커니즘

Ganoderol B is a potent α-glucosidase inhibitor. Ganoderol B has high α-glucosidase inhibition with an IC 50 of 48.5 μg/mL (119.8 μM).

보관 조건

Protected from light,Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

INHIBITOR

순수함

≥97%

이름과 식별자

• 정식 스마일: CC(CCC=C(C)CO)C1CCC2(C1(CC=C3C2=CCC4C3(CCC(C4(C)C)O)C)C)C
• IUPAC Name: (3S,5R,10S,13R,14R,17R)-17-[(E,2R)-7-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-ol
• InChIKey: AOXXVRDKZLRGTJ-AZIDVCJLSA-N
• INCHI: 1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1
• 이성체 SMILES: C[C@H](CC/C=C(\C)/CO)[C@H]1CC[C@@]2([C@@]1(CC=C3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C
• 대체 CAS: 104700-96-1
• PubChem CID: 13934286
• MeSH 용어: ganoderol B
• 분자량: 440.70

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • 분류 Prenol lipids
      • Subclass Triterpenoids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• 분류: Prenol lipids
• Subclass: Triterpenoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Triterpenoids
• Alternative Parents: Dihydroxy bile acids, alcohols and derivatives 3-hydroxy delta-7-steroids 3-beta-hydroxysteroids 14-alpha-methylsteroids Delta-7-steroids Fatty alcohols Secondary alcohols Cyclic alcohols and derivatives Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Triterpenoid - 26-hydroxysteroid - Dihydroxy bile acid, alcohol, or derivatives - Hydroxy bile acid, alcohol, or derivatives - Cholane-skeleton - Bile acid, alcohol, or derivatives - 3-hydroxy-delta-7-steroid - 3-hydroxysteroid - 14-alpha-methylsteroid - Hydroxysteroid - 3-beta-hydroxysteroid - Delta-7-steroid - Steroid - Fatty alcohol - Fatty acyl - Cyclic alcohol - Secondary alcohol - Hydrocarbon derivative - Alcohol - Organooxygen compound - Primary alcohol - Organic oxygen compound - Aliphatic homopolycyclic compound
• 설명: This compound belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

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BCHE Tclin Butyrylcholinesterase (7174 Activities)

Discover Target: BCHE

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PC-3 (62116 Activities)

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HepG2 (196354 Activities)

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LNCaP (8286 Activities)

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관련 대상(비인간)

Rattus norvegicus (775804 Activities)

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작용 메커니즘

화학 및 물리적 특성

• 분자량: 440.700 g/mol
• XLogP3: 7.400
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 440.365 Da
• Monoisotopic Mass: 440.365 Da
• Topological Polar Surface Area: 40.500 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 832.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 7
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 104700-96-1, the molecular formula is C30H48O2, and the molecular weight is 440.70 g/mol. InChIKey AOXXVRDKZLRGTJ-AZIDVCJLSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.