Carrier Free, ExactAb™, Azide Free, Validated, High Performance, See COA Azide Free,Carrier Free,ExactAb™,High Performance,Validated 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.
Store at -20°C,Avoid repeated freezing and thawing Ice chest + Ice pads 출고. 정확한 사양은 로트별 COA를 확인하세요.
SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.
크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.
Mouse anti Human HDAC1 Antibody, Monoclonal (E22), could be used for WB, IHC, IF, ICC and so on.
Application:
WB: 0.2-2μg/mL
IHC: 5-20μg/mL
ICC/IF: 5-20μg/mL
Protein Function
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Deacetylates 'Lys-310' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B.
Post-translational
Sumoylated on Lys-444 and Lys-476; which promotes enzymatic activity. Desumoylated by SENP1.
Phosphorylation on Ser-421 and Ser-423 promotes enzymatic activity and interactions with NuRD and SIN3 complexes.
Ubiquitinated by CHFR, leading to its degradation by the proteasome.
HDAC1 Mouse mAb (Ab107009) - Western Blot
All lanes: HDAC1 Mouse mAb (Ab107009) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution
Predicted band size: 62 kDa
Observed band size: 63 kDa
Exposure time: 1.2 s
HDAC1 Mouse mAb (Ab107009) - IHC
DAB staining on IHC
Sample: Human Placenta Tissue
Primary Ab: 10ug/mL HDAC1 Mouse mAb (Ab107009)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
HDAC1 Mouse mAb (Ab107009) - IHC
DAB staining on IHC
Sample: Human Lung cancer Tissue
Primary Ab: 10ug/mL HDAC1 Mouse mAb (Ab107009)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
HDAC1 Mouse mAb (Ab107009) - IHC
DAB staining on IHC
Sample: Rat Colon Tissue
Primary Ab: 10ug/mL HDAC1 Mouse mAb (Ab107009)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
HDAC1 Mouse mAb (Ab107009) - IHC
DAB staining on IHC
Sample: Rat Testis Tissue
Primary Ab: 10ug/mL HDAC1 Mouse mAb (Ab107009)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
HDAC1 Mouse mAb (Ab107009) - IHC
DAB staining on IHC
Sample: Mouse Pancreas Tissue
Primary Ab: 10ug/mL HDAC1 Mouse mAb (Ab107009)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
HDAC1 Mouse mAb (Ab107009) - IHC
DAB staining on IHC
Sample: Mouse Cerebellum Tissue
Primary Ab: 10ug/mL HDAC1 Mouse mAb (Ab107009)
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
5-20 µg/mL
0.2-2 µg/mL
5-20 µg/mL
위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
 ZJ24F0911358 | Certificate of Analysis | Jul 14, 2026 | Ab107009 |
| ZJ23F0800907 | Certificate of Analysis | Aug 25, 2023 | Ab107009 |
| ZJ23F0800909 | Certificate of Analysis | Aug 25, 2023 | Ab107009 |
당사의 등급 선택 가이드는 카탈로그의 모든 변형 제품에 대해 순도, 안정제 상태 및 용도 적합성을 다룹니다.
Carrier Free 등급 가이드 보기 → Validated 등급 가이드 보기 → ExactAb™ 등급 가이드 보기 → Azide Free 등급 가이드 보기 → High Performance 등급 가이드 보기 →
