Icariin - 10mM in DMSO , CAS No.489-32-7

CAS: 489-32-7 Cat. No.: I407996 분자식: C₃₃H₄₀O₁₅ 분자량: 676.66 EC 번호: 610-440-0 PubChem CID: 5318997

GRADE & PURITY 10mM in DMSO

Synonyms

4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Icariin is a cGMP-specificPDE5inhibitor withIC50of 0.432 μM, 167-fold more selective for PDE5 than PDE4.
In vitro

In vivo

Cell Data

cell lines：PC-3 cells

Concentrations：

Incubation Time：

Powder Purity:≥97%

Specifications

동의어

4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

Icariin is a cGMP-specific PDE5 inhibitor with IC50 of 0.432 μM, 167-fold more selective for PDE5 than PDE4.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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이름과 식별자

이성체 SMILES

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O

WGK 독일

3

PubChem CID

5318997

분자량

676.66

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 74 mg/mL (200.29 mM)
• 특정 회전[α]: -84° (C=1,Pyridine)
• 녹는점(°C): 235 - 239°C

자주 묻는 질문

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 489-32-7, the molecular formula is C33H40O15, and the molecular weight is 676.66 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.