Ilaprazole sodium - ≥98% , CAS No.172152-50-0

CAS: 172152-50-0 Cat. No.: I413292 분자식: C₁₉H₁₇N₄NaO₂S 분자량: 388.42

등급 & 순도 ≥98%

Synonyms

AKOS037515492 | HY-B2145 | 1H-Benzimidazole, 2-(((4-methoxy-3-methyl-2-pyridinyl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-, sodium salt (1:1) | Ilaprazole sodium | sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide | IY-8

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Information

Ilaprazole sodium Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation.

Targets

Proton pump ; H(+)/K(+)-ATPase (in rabbit parietal cell preparation) ; 6 μM

사양

동의어

AKOS037515492 | HY-B2145 | 1H-Benzimidazole, 2-(((4-methoxy-3-methyl-2-pyridinyl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-, sodium salt (1:1) | Ilaprazole sodium | sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide | IY-8

사양 및 순도

≥98%

생화학 및 생리적 메커니즘

Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥98%

제품 특성

ALogP

3.414

hba_count

4

회전 가능한 결합

5

이름과 식별자

Pubchem Sid

488202692

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488202692

정식 스마일

CC1=C(C=CN=C1CS(=O)C2=NC3=C([N-]2)C=C(C=C3)N4C=CC=C4)OC.[Na+]

IUPAC Name

sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide

InChIKey

ZQGDDMFDBZPGCD-UHFFFAOYSA-N

INCHI

1S/C19H17N4O2S.Na/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23;/h3-11H,12H2,1-2H3;/q-1;+1

이성체 SMILES

CC1=C(C=CN=C1CS(=O)C2=NC3=C([N-]2)C=C(C=C3)N4C=CC=C4)OC.[Na+]

분자량

388.42

Reaxy-Rn

21526395

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21526395&ln=

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 78 mg/mL (200.81 mM)
• DMSO(mg/mL) 최대 용해도: 78
• DMSO(mM) 최대 용해도: 200.81355234025
• 물(mg/mL) 최대 용해도: -1