Iodoacetamide - Moligand™, 10mM in DMSO , Activator of TRPA1, CAS No.144-48-9, Activator of TRPA1

Name: Iodoacetamide - Moligand™, 10mM in DMSO , Activator of TRPA1, CAS No.144-48-9, Activator of TRPA1
SKU: I421630
Availability: InStock

CAS: 144-48-9 Cat. No.: I421630 분자식: C₂H₄INO 분자량: 184.96 Beilstein Registry Number: 1739080 EC 번호: 205-630-1

112 Citations COA

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Iodoacetamide - Moligand™, 10mM in DMSO CAS No(144-48-9) by Aladdin Scientific

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주문 가능

GRADE & PURITY Moligand™ ? 10mM in DMSO

Synonyms

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요 Specifications 이름과 식별자 Documentation Advanced Data Taxonomic Classification 3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 자주 묻는 질문과 기사 Citations of This Product 솔루션 계산기 리뷰

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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 112 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Alkylating reagent for cysteine residues in peptide sequencing.

Specifications

동의어

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Alkylating agent used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

등급

Moligand™

작업 유형

ACTIVATOR

작동 메커니즘

Activator of TRPA1

이름과 식별자

Pubchem Sid

528774185

정식 스마일

C(C(=O)N)I

IUPAC Name

2-iodoacetamide

InChIKey

PGLTVOMIXTUURA-UHFFFAOYSA-N

INCHI

1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)

이성체 SMILES

C(C(=O)N)I

WGK 독일

RTECS

AC4200000

UN 번호

2811

포장 그룹

III

분자량

184.96

Beilstein

1739080

Reaxy-Rn

1739080

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1739080&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - 분류 Carboxylic acids and derivatives
    - Subclass Carboxylic acid derivatives
      - Level5 Carboxylic acid amides
        Level6 Primary carboxylic acid amides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
분류	Carboxylic acids and derivatives
Subclass	Carboxylic acid derivatives
Intermediate Tree Nodes	Carboxylic acid amides
Direct Parent	Primary carboxylic acid amides
Alternative Parents	Organopnictogen compounds Organonitrogen compounds Organoiodides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl iodides
Molecular Framework	Aliphatic acyclic compounds
Substituents	Primary carboxylic acid amide - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organoiodide - Organohalogen compound - Carbonyl group - Alkyl iodide - Alkyl halide - Aliphatic acyclic compound
설명	This compound belongs to the class of organic compounds known as primary carboxylic acid amides. These are compounds comprising primary carboxylic acid amide functional group, with the general structure RC(=O)NH2.
External Descriptors	an iodide
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

관련 대상(비인간)

Saccharomyces cerevisiae (19171 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trpa1 Transient receptor potential cation channel subfamily A member 1 (1003 Activities)

Discover Target: Trpa1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

pfk 6-phospho-1-fructokinase (7870 Activities)

Discover Target: pfk

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)

Discover Target: fba

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FTL Ferritin light chain (43324 Activities)

Discover Target: FTL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

crtY Lycopene cyclase (9 Activities)

Discover Target: crtY

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

인증서(CoA, COO, BSE/TSE 및 분석 차트)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number	Certificate Type	날짜	항목
I2410031	Certificate of Analysis	Jul 10, 2026	I421630

화학 및 물리적 특성

감도	Light & Moisture Sensitive
녹는점(°C)	95°C
분자량	184.960 g/mol
XLogP3	-0.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	184.934 Da
Monoisotopic Mass	184.934 Da
Topological Polar Surface Area	43.100 Å²
Heavy Atom Count	5
Formal Charge	0
Complexity	44.900
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

자주 묻는 질문과 기사

Common Reagents for Reducing Protein Disulfide Bonds

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Reducible protein Protein disulfide bond

A Practical Guide to Small-Molecule Chemical Probes: Concept Clarification, Causal Validation, and Experimental Selection (with Product Navigation and Tables A–D)

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Chemical probe Small-Molecule Chemical Probes

Endoproteinase Lys-C: Mechanism, Applications, and Method-Control Considerations for Lysine-Specific Digestion

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Peptide Mapping Serine protease Lys-C Endoproteinase Lys-C Lysine-specific cleavage Denaturing digestion LC–MS Sequence coverage Missed cleavage rate Critical peptide monitoring Method validation

Plant Omics Panorama: Workflow Frameworks and Multi-Omics Integration from Genomics to Transcriptomics, Proteomics, and Metabolomics

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Proteomics Plant omics Genomics Transcriptomics Metabolomics Multi-omics integration Phenomics Epigenomics

Bromelain: Enzymological Properties and Key Points for Food, Pharmaceutical, and Industrial Applications

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Cysteine protease bromelain proteolysis BAEE fibrin meat tenderization

Methionine: Biological Roles and Key Points for Research Application

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

glutathione one-carbon metabolism SAM Redox homeostasis methionine SAH methylation homocysteine transsulfuration pathway

Review of Chymotrypsin: Enzymological Properties, Catalytic Mechanism, and Research Applications

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Peptide Mapping Serine protease substrate specificity limited proteolysis catalytic triad Chymotrypsin Alpha-Chymotrypsin Oxyanion Hole Acyl-Enzyme Intermediate Methodological Quality Control

Clostridial Proteases: Classification, Molecular Mechanisms, and Research Applications

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

clostridial proteases

Glycoprotein Hormone Family: Molecular Features, Signaling Bias, and In Vivo Pharmacokinetics

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Glycosylation Pharmacokinetics FSH LH hCG TSH Glycoprotein hormones Common α-subunit Specific β-subunit Signaling bias

Methodological Studies on Glycoprotein Structural Characterization and Quality Attribute Analysis

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Glycosylation Glycoprotein Quality Attributes Critical Quality Attributes Released Glycan Analysis Glycopeptide Analysis Intact Mass Spectrometry Higher-Order Structure Multi-Attribute Method Comparability Study

Research Framework for Multi-Enzyme Digestion Strategies and Optimization of Proteomic Coverage

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Proteomics Mass spectrometry Multi-Enzyme Digestion Coverage Optimization Proteolytic Strategy Peptide Detectability Sample Complexity Research Framework

Thiol and Disulfide Status in Biological Samples: Detection Methods and Applications

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

glutathione disulfide bonds DTNB Thiol redox state Ellman assay protein thiol GSH/GSSG

Neuropathological Mechanisms of Cerebral Infarction

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Oxidative Stress neuroinflammation blood-brain barrier cerebral infarction ischemic stroke neuropathological mechanism ischemic penumbra excitotoxicity

Summary of Research Advances in Oxidative Stress

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

ROS Oxidative Stress Nrf2 ferroptosis non-coding RNA mitochondrial oxidative stress redox proteomic precision antioxidant therapy

Regulatory Mechanisms, Research Methods, and Modification-Omics Analysis of Protein Post-Translational Modifications

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Glycosylation methylation SUMOylation Protein Post-Translational Modifications Ubiquitination Phosphorylation Acetylation Lactylation Modification Proteomics

Why Proximity to Cysteine Does Not Necessarily Lead to Covalent Bond Formation: Warhead Reactivity, Reaction Geometry, and Target-Site Microenvironment

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Cysteine Covalent Inhibition

Citations of This Product

How to Cite Aladdin Scientific Products? Citations Search

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리뷰

📚 Citations by Application

Other applications52

Controlled-release & nanoparticle carrier3

Drug / compound screening20

Cell viability8

Organic synthesis — reaction medium34

Nanoparticle / material biocompatibility1

Chromatography (HPLC / GC / TLC)22

Spectroscopy sample preparation15

Topical & ophthalmic formulation2

Extraction & workup solvent42

Industrial & non-pharma application2

Cell proliferation4

Cytotoxicity screening8

Polymer synthesis & polymerization1

Cancer cell line characterization1

View all 112 citations →

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Iodoacetamide - Moligand™, 10mM in DMSO , Activator of TRPA1, CAS No.144-48-9, Activator of TRPA1

Storage & shipping

Quality documents

Literature proof

개요

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

고객 리뷰

📚 Citations by Application

Need help choosing the grade?

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