ITH 12575 - ≥98% , CAS No.1802013-08-6

CAS: 1802013-08-6 Cat. No.: I287169 분자식: C18H18ClNOS 분자량: 331.86
주문 가능
GRADE & PURITY ≥98%
Synonyms
7-Chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-4,1-benzothiazepin-2(3H)-one
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
독일 (EU)*
Price
Qty
1mg
I287169-1mg
주문제작 · 8~12주
US$68.90
5mg
I287169-5mg
3 재고 있음
—
US$244.90
10mg
I287169-10mg
3 재고 있음
—
US$390.90
25mg
I287169-25mg
3 재고 있음
—
US$781.90
50mg
I287169-50mg
2 재고 있음
—
US$1,249.90
100mg
I287169-100mg
1 재고 있음
—
US$1,999.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

ITH-12575 is an inhibitor of Mitochondrial Na+/Ca2+ exchange (mNCX). ITH12575 reduces Ca(2+) influx through CALHM1 at low micromolar concentrations.

Specifications

동의어
7-Chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-4,1-benzothiazepin-2(3H)-one
사양 및 순도
≥98%
생화학 및 생리적 메커니즘
ITH12575 is apotent and selective inhibitor of mitochondrial Na+/Ca2+ exchanger mNCX with neuroprotective activity. It was shown to reduce Ca2+ efflux from the mitochondria to the cytosol with an EC50 value of 690 nM and was shown to protect against Ca2+
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
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작업 유형
INHIBITOR
순수함
≥98%
이름과 식별자
Pubchem Sid528764920
정식 스마일CC(C)C1=CC=CC=C1C2C3=C(C=CC(=C3)Cl)NC(=O)CS2
IUPAC Name7-chloro-5-(2-propan-2-ylphenyl)-1,5-dihydro-4,1-benzothiazepin-2-one
InChIKeyRDMUJSJZBYAAEF-UHFFFAOYSA-N
INCHI1S/C18H18ClNOS/c1-11(2)13-5-3-4-6-14(13)18-15-9-12(19)7-8-16(15)20-17(21)10-22-18/h3-9,11,18H,10H2,1-2H3,(H,20,21)
분자량 331.86
Reaxy-Rn 28321041
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28321041&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D 구조
상호 작용 화학 구조 모델





인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate Type날짜항목
G2415285Certificate of AnalysisApr 07, 2024 I287169
G2415286Certificate of AnalysisApr 07, 2024 I287169
G2415287Certificate of AnalysisApr 07, 2024 I287169
G2415288Certificate of AnalysisApr 07, 2024 I287169
G2415289Certificate of AnalysisApr 07, 2024 I287169
G2415290Certificate of AnalysisApr 07, 2024 I287169
G2415291Certificate of AnalysisApr 07, 2024 I287169
G2415293Certificate of AnalysisApr 07, 2024 I287169
G2415294Certificate of AnalysisApr 07, 2024 I287169
G2415296Certificate of AnalysisApr 07, 2024 I287169
화학 및 물리적 특성
용해성Solvent:DMSO, Max Conc. mg/mL: 33.19, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 6.64, Max Conc. mM: 20
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