IXA4 - Moligand™, ≥98% , CAS No.1185329-96-7

CAS: 1185329-96-7 Cat. No.: I651766 분자식: C₂₄H₂₈N₄O₄ 분자량: 436.50 EC 번호: 840-577-3 PubChem CID: 26357859

등급 & 순도 Moligand™, ≥98%

Synonyms

N-(1-(2-(Methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation.

사양

동의어

N-(1-(2-(Methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide

사양 및 순도

Moligand™, ≥98%

생화학 및 생리적 메커니즘

IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stre

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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등급

Moligand™

작업 유형

INHIBITOR

순수함

≥98%

이름과 식별자

이성체 SMILES

CC1=CC=C(C=C1)OCCN(C)C(=O)CN2C=C(C=N2)NC(=O)CCOC3=CC=CC=C3

PubChem CID

26357859

분자량

436.50

화학 및 물리적 특성

• 용해성: DMSO : 100 mg/mL (229.10 mM; Need ultrasonic)
• 분자량: 436.500 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 11
• Exact Mass: 436.211 Da
• Monoisotopic Mass: 436.211 Da
• Topological Polar Surface Area: 85.700 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 576.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1