JNJ 0966 - 10mM in DMSO , CAS No.315705-75-0

CAS: 315705-75-0 Cat. No.: J423286 분자식: C16H16N4O2S2 분자량: 360.45
주문 가능
GRADE & PURITY 10mM in DMSO
Synonyms
N-[2-[(2-Methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]acetamide
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
USA
독일 (EU)*
Price
Qty
1ml
J423286-1ml
1 재고 있음
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US$164.90

US$241.90
저장 US$77.00 (31.83%)
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

동의어
N-[2-[(2-Methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]acetamide
사양 및 순도
10mM in DMSO
생화학 및 생리적 메커니즘
Pro-MMP9 activation inhibitor (IC50= 440 nM). Inhibits the conversion of pro-MMP9 to active MMP9, without directly affecting MMP9 enzymatic activity. Exhibits selectivity for pro-MMP9 over pro-MMP1, 2 and 3. Inhibits cell invasion inin vitroassays. Reduce
보관 조건
Store at -80°C
배송
Dry ice packs + Cold packs
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작업 유형
INHIBITOR
이름과 식별자
Pubchem Sid
정식 스마일
CC1=C(SC(=N1)NC(=O)C)C2=CSC(=N2)NC3=CC=CC=C3OC
IUPAC Name
N-[5-[2-(2-methoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
InChIKey
ZADCDCMLLGDCRM-UHFFFAOYSA-N
INCHI
1S/C16H16N4O2S2/c1-9-14(24-16(17-9)18-10(2)21)12-8-23-15(20-12)19-11-6-4-5-7-13(11)22-3/h4-8H,1-3H3,(H,19,20)(H,17,18,21)
이성체 SMILES
CC1=C(SC(=N1)NC(=O)C)C2=CSC(=N2)NC3=CC=CC=C3OC
분자량
360.45
Reaxy-Rn
12373585
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=12373585&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
분류Organonitrogen compounds
SubclassN-arylamides
Intermediate Tree Nodes Not available
Direct ParentN-acetylarylamines
Alternative Parents Methoxyanilines  2,4,5-trisubstituted thiazoles  Phenoxy compounds  Methoxybenzenes  Anisoles  2,4-disubstituted thiazoles  Alkyl aryl ethers  2-amino-1,3-thiazoles  Acetamides  Heteroaromatic compounds  Amino acids and derivatives  Secondary carboxylic acid amides  Azacyclic compounds  Secondary amines  Hydrocarbon derivatives  Organic oxides  Organopnictogen compounds  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents N-acetylarylamine - Methoxyaniline - Phenoxy compound - 2,4,5-trisubstituted 1,3-thiazole - Anisole - Phenol ether - Aniline or substituted anilines - Methoxybenzene - 2,4-disubstituted 1,3-thiazole - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - 1,3-thiazol-2-amine - Acetamide - Thiazole - Azole - Heteroaromatic compound - Amino acid or derivatives - Secondary carboxylic acid amide - Carboxamide group - Azacycle - Organoheterocyclic compound - Secondary amine - Carboxylic acid derivative - Ether - Organic oxide - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organooxygen compound - Amine - Organopnictogen compound - Aromatic heteromonocyclic compound
설명This compound belongs to the class of organic compounds known as n-acetylarylamines. These are acetamides where one or more amide hydrogens is substituted by an aryl group.
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





관련 대상(인간)
MMP9 Tchem Matrix metalloproteinase-9 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HT-1080 (3966 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
관련 대상(비인간)
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
분자량360.500 g/mol
XLogP33.400
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass360.071 Da
Monoisotopic Mass360.071 Da
Topological Polar Surface Area133.000 Ų
Heavy Atom Count24
Formal Charge0
Complexity442.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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