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KS106 - ≥99% , CAS No.2408477-50-7
주문 가능
GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice
Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Protected from light,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요
KS106 is a potent ALDH inhibitor with IC 50 s of 334, 2137, 360 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS106 induces apoptosis and cell cycle arrest at the G2/M phase
In Vitro
KS106 (compound 3h) (0-100 µM; 72 h) shows anti-proliferative activity with IC 50 s of 5.7, 5.7, 5.7, 4.9, 1.5, 2.6, 1.6, 1.7, 2.2, 20.7 µM for UACC 903, 1205 Lu, HCT116, HT29, NCIH929, U266, RPMI8226, MM.1R, MM.1S, FF2441 cells, respectively. KS106 (5 µM, 24 h) induces apoptosis and cell cycle arrest at the G2/M phase. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Apoptosis AnalysisCell Line: HCT116, HT29 cells Concentration: 5 µM Incubation Time: 24 h Result: Induced cell apoptosis. Cell Cycle AnalysisCell Line: HCT116 cells Concentration: 5 µM Incubation Time: 24 h Result: Induced cell cycle arrest at G2/M phase.
Form:Solid
IC50& Target:ALDH1 ALDH2 ALDH3
Specifications
사양 및 순도
≥99%
생화학 및 생리적 메커니즘
KS106 is a potent ALDH inhibitor with IC 50 s of 334, 2137, 360 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation and t
보관 조건
Store at 2-8°C,Protected from light,Desiccated
배송
Wet ice
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작업 유형
INHIBITOR
순수함
≥99%
이름과 식별자
| 분자량 | 474.29 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
| 용해성 | DMSO : 100 mg/mL (210.84 mM; Need ultrasonic) |
|---|
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리뷰
고객 리뷰
자주 묻는 질문
What is the purity of this product?
This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at 2–8 °C, protected from light, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2408477-50-7, the molecular formula is C18H15BrF3N3O2S, and the molecular weight is 474.29 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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