Lappaconite HBr - 10mM in DMSO , CAS No.97792-45-5

CAS: 97792-45-5 Cat. No.: L409001 분자식: C₃₂H₄₄N₂O₈·HBr 분자량: 665.62 EC 번호: 808-132-8 PubChem CID: 51346120

GRADE & PURITY 10mM in DMSO

Synonyms

Aconitane-4,8,9-triol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], hydrobromide (1:1), (1α,14α,16β)-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.
In vitro

Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects. Its absorption percentage in rat stomachs after administration was 9.67%.The absorption percentages at duodenum,jejunum,ileum and colon were 19.61%,11.83%,12.95% and 9.51%, respectively.When the concentration was raised from 10 mg/L to 40 mg/L, the uptake of lappaconite hydrobromide was linearly increased,whereas the absorption rate constant kept at the same level.

In vivo

LD50: Mice 10.5mg/kg (i.p.); Rats 9.9mg/kg (i.p.)
Cell Data

cell lines：HPAF-II, PaTu 8988S, and Capan-2 cells

Concentrations：

Incubation Time：

Powder Purity:≥95%

Specifications

동의어

Aconitane-4,8,9-triol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], hydrobromide (1:1), (1α,14α,16β)-

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

이름과 식별자

이성체 SMILES

CCN1C[C@@]2(CC[C@@H]([C@@]34[C@@H]2C[C@@H](C31)[C@]5(C[C@@H]([C@H]6C[C@@H]4[C@@]5([C@H]6OC)O)OC)O)OC)OC(=O)C7=CC=CC=C7NC(=O)C.Br

PubChem CID

51346120

분자량

665.62

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 97 mg/mL (200.89 mM); Ethanol: 97 mg/mL (200.89 mM); Water: Insoluble
• 녹는점(°C): 222 °C