lartesertib - Moligand™ , Inhibitor of ATM serine/threonine kinase;Inhibitor of protein kinase; DNA-activated; catalytic subunit, CAS No.2020089-41-0, Inhibitor of ATM serine/threonine kinase;Inhibitor of protein kinase; DNA-activated; catalytic subunit

CAS: 2020089-41-0 Cat. No.: L611450 PubChem CID: 122599280

등급 & 순도 Moligand™

Synonyms

Lartesertib | 2495096-26-7 | M 4076 [WHO-DD] | EX-A6934 | BDBM418555 | MS-28119 | 8-(1,3-Dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydro2H-imidazo[4,5-c]quinolin-2-one | 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-flu

Storage

Room temperature

사양

동의어

Lartesertib | 2495096-26-7 | M 4076 [WHO-DD] | EX-A6934 | BDBM418555 | MS-28119 | 8-(1,3-Dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydro2H-imidazo[4,5-c]quinolin-2-one | 8-(1,3-dimethyl-1H-pyrazol-4-yl)-1-(3-flu

사양 및 순도

Moligand™

보관 조건

Room temperature

등급

Moligand™

작업 유형

INHIBITOR

작동 메커니즘

Inhibitor of ATM serine/threonine kinase;Inhibitor of protein kinase; DNA-activated; catalytic subunit

이름과 식별자

정식 스마일

Cc1nn(cc1c1c(cc2c(c1)c1c(cn2)n(c(=O)n1c1c(cncc1OC)F)C)OC)C

IUPAC Name

8-(1,3-dimethylpyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methylimidazo[4,5-c]quinolin-2-one

InChIKey

WNEFOSMCGCLLJU-UHFFFAOYSA-N

INCHI

1S/C23H21FN6O3/c1-12-15(11-28(2)27-12)13-6-14-17(7-19(13)32-4)26-9-18-21(14)30(23(31)29(18)3)22-16(24)8-25-10-20(22)33-5/h6-11H,1-5H3

이성체 SMILES

CC1=NN(C=C1C2=C(C=C3C(=C2)C4=C(C=N3)N(C(=O)N4C5=C(C=NC=C5OC)F)C)OC)C

PubChem CID

122599280

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 분류 Quinolines and derivatives
      • Subclass Imidazoquinolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 분류: Quinolines and derivatives
• Subclass: Imidazoquinolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Imidazoquinolines
• Alternative Parents: Imidazo-[4,5-c]pyridines Anisoles Pyridinones Alkyl aryl ethers N-substituted imidazoles Aryl fluorides Pyrazoles Heteroaromatic compounds Ureas Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Imidazoquinoline - Imidazo-[4,5-c]pyridine - Imidazopyridine - Anisole - Pyridinone - Alkyl aryl ether - Benzenoid - Pyridine - N-substituted imidazole - Aryl halide - Aryl fluoride - Heteroaromatic compound - Pyrazole - Imidazole - Azole - Urea - Azacycle - Ether - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Aromatic heteropolycyclic compound
• 설명: This compound belongs to the class of organic compounds known as imidazoquinolines. These are aromatic heterocyclic compounds containing an imidazole ring fused to a quinoline ring system. In some configurations, the imidazole ring shares a nitrogen atom with the quinoline moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

PRKDC Tchem DNA-dependent protein kinase catalytic subunit (0 Activities)

Discover Target: PRKDC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ATM Tchem Serine-protein kinase ATM (0 Activities)

Discover Target: ATM

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

자주 묻는 질문

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2020089-41-0. InChIKey WNEFOSMCGCLLJU-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.