LDN 193188 - ≥99%(HPLC) , CAS No.1267610-30-9

CAS: 1267610-30-9 Cat. No.: L287465 분자식: C₂₀H₁₇Cl₂N₅O₄S 분자량: 494.35

GRADE & PURITY ≥99%(HPLC)

Synonyms

2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Product Describtion:

Inhibitor of phosphatidylcholine transfer protein (PC-TP)

Specifications

동의어

2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide

사양 및 순도

≥99%(HPLC)

생화학 및 생리적 메커니즘

Inhibitor of phosphatidylcholine transfer protein (PC-TP). Regulates hepatic glucose metabolism. Also promotes insulin-independent phosphorylation of key insulin signaling molecules.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥99%(HPLC)

이름과 식별자

Pubchem Sid

504771867

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504771867

정식 스마일

CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C

IUPAC Name

2,4-dichloro-N-[[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]carbamoyl]benzamide

InChIKey

COTBDKMEUUNJTI-UHFFFAOYSA-N

INCHI

1S/C20H17Cl2N5O4S/c1-11-9-12(2)24-19(23-11)27-32(30,31)15-6-4-14(5-7-15)25-20(29)26-18(28)16-8-3-13(21)10-17(16)22/h3-10H,1-2H3,(H,23,24,27)(H2,25,26,28,29)

이성체 SMILES

CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C

분자량

494.35

Reaxy-Rn

21195324

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21195324&ln=

관련 대상(인간)

STARD7 Tbio StAR-related lipid transfer protein 7, mitochondrial (7 Activities)

Discover Target: STARD7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PCTP Tbio Phosphatidylcholine transfer protein (43 Activities)

Discover Target: PCTP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 용해성: Solvent:DMSO, Max Conc. mg/mL: 49.44, Max Conc. mM: 100
• 분자량: 494.300 g/mol
• XLogP3: 4.100
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 493.038 Da
• Monoisotopic Mass: 493.038 Da
• Topological Polar Surface Area: 139.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 762.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product, and how is it determined?

This product is supplied at ≥99% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1267610-30-9, the molecular formula is C20H17Cl2N5O4S, and the molecular weight is 494.35 g/mol. InChIKey COTBDKMEUUNJTI-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.