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· · COA & SDS available for every product · Same-day shipping on in-stock items Loreclezole hydrochloride - ≥98% , CAS No.2227372-56-5
Synonyms
(Z)-1-[2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole hydrochloride | R 72063 hydrochloride | R-72063 hydrochloride | 1-[(Z)-2-Chloro-2-(2,4-dichlorophenyl)vinyl]-1,2,4-triazole hydrochloride | 1-[(1Z)-2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
(Z)-1-[2-Chloro-2-(2, 4-dichlorophenyl)ethenyl]-1H-1, 2, 4-triazole hydrochloride | R 72063 hydrochloride | R-72063 hydrochloride | 1-[(Z)-2-Chloro-2-(2, 4-dichlorophenyl)vinyl]-1, 2, 4-triazole hydrochloride | 1-[(1Z)-2-Chloro-2-(2, 4-dichlorophenyl)ethenyl]-1H
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Subtype-selective GABAAreceptor modulator. Acts as a positive allosteric modulator ofβ2 orβ3-subunit containing receptors. Also acts as a negative modulator at a novel regulatory site, enhancing GABAAreceptor sensitization. Inhibits homomericρ1 GABACrecep
Storage
Store at -20°C, Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles C1=CC(=C(C=C1Cl)Cl)C(=CN2C=NC=N2)Cl.Cl IUPAC Name 1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole;hydrochloride InChIKey AWKSVFLKVCVVFQ-MDZFRNKHSA-N INCHI 1S/C10H6Cl3N3.ClH/c11-7-1-2-8(9(12)3-7)10(13)4-16-6-14-5-15-16;/h1-6H;1H/b10-4-; Isomeric SMILES C1=CC(=C(C=C1Cl)Cl)/C(=C/N2C=NC=N2)/Cl.Cl PubChem CID 45073437 Molecular Weight 310.99
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Halobenzenes Intermediate Tree Nodes Chlorobenzenes Direct Parent Dichlorobenzenes Alternative Parents Styrenes Aryl chlorides Triazoles Heteroaromatic compounds Vinyl chlorides Chloroalkenes Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organochlorides Hydrochlorides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents 1,3-dichlorobenzene - Styrene - Aryl chloride - Aryl halide - Azole - Heteroaromatic compound - 1,2,4-triazole - Azacycle - Chloroalkene - Haloalkene - Organoheterocyclic compound - Vinyl halide - Vinyl chloride - Organic nitrogen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Hydrochloride - Hydrocarbon derivative - Organopnictogen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as dichlorobenzenes. These are compounds containing a benzene with exactly two chlorine atoms attached to it. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 1.37, Max Conc. mM: 5 with gentle warming; Solvent:ethanol, Max Conc. mg/mL: 1.37, Max Conc. mM: 5 with gentle warming Molecular Weight 311.000 g/mol XLogP3 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 2 Rotatable Bond Count 2 Exact Mass 310.936 Da Monoisotopic Mass 308.939 Da Topological Polar Surface Area 30.700 Ų Heavy Atom Count 17 Formal Charge 0 Complexity 272.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 1 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 1 Covalently-Bonded Unit Count 2
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