The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
· · COA & SDS 모든 제품에 대한 사용 가능 · 주식 상품에 대한 같은 날 배송 LY2562175 - ≥99% , Bile acid receptor FXR agonist, CAS No.1103500-20-4, Bile acid receptor FXR agonist
Synonyms
SB19684 | 1103500-20-4 | AKOS040741985 | UNII-VVA2ZDV3LX | MS-29957 | TERN-101 | AC-36270 | RPVDFHPBGBMWID-UHFFFAOYSA-N | SCHEMBL1097262 | VVA2ZDV3LX | 6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-ca
Shipped In
Ice chest + Ice pads
🧪
Why this grade ≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
📋
Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요 LY2562175 is a potent and selective FXR agonist, with an EC50 of 193 nM.
Targets
human FXR (cell-based cotransfection assay) 193 nM(EC50)
Specifications 동의어
SB19684 | 1103500-20-4 | AKOS040741985 | UNII-VVA2ZDV3LX | MS-29957 | TERN-101 | AC-36270 | RPVDFHPBGBMWID-UHFFFAOYSA-N | SCHEMBL1097262 | VVA2ZDV3LX | 6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-ca
생화학 및 생리적 메커니즘
LY2562175 is a potent and selective agonist of FXR. LY2562175 promotes transcriptional activation of human FXR in a cell-based cotransfection assay with EC50 of 193 nM.
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
작동 메커니즘
Bile acid receptor FXR agonist
제품 특성 이름과 식별자 정식 스마일
CN1C=C(C2=C1C=C(C=C2)N3CCC(CC3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)C(=O)O
IUPAC Name
6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid
InChIKey
RPVDFHPBGBMWID-UHFFFAOYSA-N
INCHI
1S/C28H27Cl2N3O4/c1-32-14-20(28(34)35)19-8-7-17(13-24(19)32)33-11-9-18(10-12-33)36-15-21-26(31-37-27(21)16-5-6-16)25-22(29)3-2-4-23(25)30/h2-4,7-8,13-14,16,18H,5-6,9-12,15H2,1H3,(H,34,35)
이성체 SMILES
CN1C=C(C2=C1C=C(C=C2)N3CCC(CC3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)C(=O)O
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20184274&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds 분류 Indoles and derivatives Subclass Indolecarboxylic acids and derivatives Intermediate Tree Nodes Not available Direct Parent Indolecarboxylic acids and derivatives Alternative Parents N-alkylindoles Indoles Pyrrole carboxylic acids 5-cyclopropylisoxazoles Dichlorobenzenes Dialkylarylamines Piperidines N-methylpyrroles Aryl chlorides Vinylogous amides Heteroaromatic compounds Amino acids Oxacyclic compounds Dialkyl ethers Carboxylic acids Azacyclic compounds Hydrocarbon derivatives Organic oxides Organochlorides Molecular Framework Aromatic heteropolycyclic compounds Substituents Indolecarboxylic acid derivative - N-alkylindole - Indole - 5-cyclopropylisoxazole - Cyclopropylisoxazole - 1,3-dichlorobenzene - Pyrrole-3-carboxylic acid - Pyrrole-3-carboxylic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Halobenzene - Chlorobenzene - N-methylpyrrole - Aryl chloride - Aryl halide - Piperidine - Substituted pyrrole - Monocyclic benzene moiety - Benzenoid - Azole - Heteroaromatic compound - Pyrrole - Isoxazole - Vinylogous amide - Amino acid or derivatives - Amino acid - Tertiary amine - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Azacycle - Dialkyl ether - Ether - Organic oxygen compound - Organic nitrogen compound - Amine - Organic oxide - Organooxygen compound - Hydrocarbon derivative - Organonitrogen compound - Organochloride - Organohalogen compound - Aromatic heteropolycyclic compound 설명 This compound belongs to the class of organic compounds known as indolecarboxylic acids and derivatives. These are compounds containing a carboxylic acid group (or a derivative thereof) linked to an indole. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 용해성 Solubility (25°C) In vitro DMSO: 100 mg/mL (185.03 mM); Ethanol: 1.5 mg/mL (2.77 mM); Water: Insoluble; 분자량 540.400 g/mol XLogP3 5.500 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 7 Exact Mass 539.138 Da Monoisotopic Mass 539.138 Da Topological Polar Surface Area 80.700 Ų Heavy Atom Count 37 Formal Charge 0 Complexity 800.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
솔루션 계산기 Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator 리뷰
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our
Cookie Policy. 설정 모두 동의 Decline
Shall we send you a message when we have discounts available?
Remind me later Allow
Thank you! Please check your email inbox to confirm.
Oops! Notifications are disabled.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.
G2411237