LY3405105 - ≥95% , CAS No.2326428-25-3

CAS: 2326428-25-3 Cat. No.: L413667 분자식: C₂₆H₃₉N₇O₃ 분자량: 497.63

GRADE & PURITY ≥95%

Synonyms

1-​Piperidinecarboxylic acid,4-​[[5-​methyl-​3-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyrimidin-​7-​yl]​amino]​-​,1-​[(2E)​-​4-​(dimethylamino)​-​1-​oxo-​2-​buten-​1-​yl]​-​3-​pyrrolidinyl ester

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Information

LY3405105 LY3405105 is an orally active CDK7 inhibitor with an IC50 of 92.8 nM. LY3405105 shows potential antineoplastic activity.

Specifications

동의어

1-​Piperidinecarboxylic acid,4-​[[5-​methyl-​3-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyrimidin-​7-​yl]​amino]​-​,1-​[(2E)​-​4-​(dimethylamino)​-​1-​oxo-​2-​buten-​1-​yl]​-​3-​pyrrolidinyl ester

사양 및 순도

≥95%

생화학 및 생리적 메커니즘

LY3405105 is an orally active CDK7 inhibitor with an IC50 of 92.8 nM. LY3405105 shows potential antineoplastic activity.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

INHIBITOR

순수함

≥95%

이름과 식별자

• Pubchem Sid: 504773536
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773536
• 정식 스마일: CC1=NC2=C(C=NN2C(=C1)NC3CCN(CC3)C(=O)OC4CCN(C4)C(=O)C=CCN(C)C)C(C)C
• IUPAC Name: [1-[(E)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl] 4-[(5-methyl-3-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-yl)amino]piperidine-1-carboxylate
• InChIKey: GRDAHPJRLCTJNA-VOTSOKGWSA-N
• INCHI: 1S/C26H39N7O3/c1-18(2)22-16-27-33-23(15-19(3)28-25(22)33)29-20-8-12-31(13-9-20)26(35)36-21-10-14-32(17-21)24(34)7-6-11-30(4)5/h6-7,15-16,18,20-21,29H,8-14,17H2,1-5H3/b7-6+
• 분자량: 497.63
• Reaxy-Rn: 34497862
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34497862&ln=

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 99 mg/mL (198.94 mM); Ethanol: 99 mg/mL (198.94 mM); Water: Insoluble