MAC glucuronide linker-2 - Moligand™, ≥99% , CAS No.229977-57-5

CAS: 229977-57-5 Cat. No.: M649497 분자식: C₂₀H₂₅NO₁₁ 분자량: 455.42

GRADE & PURITY Moligand™, ≥99%

Synonyms

Methyl 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronate | 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronic Acid Methyl Ester

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

개요

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

Form:Solid

IC50& Target:Cleavable Glycosidase Cleavable

Specifications

동의어

Methyl 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronate | 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronic Acid Methyl Ester

사양 및 순도

Moligand™, ≥99%

생화학 및 생리적 메커니즘

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

보관 조건

Store at -20°C,Argon charged,Desiccated

배송

Ice chest + Ice pads

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등급

Moligand™

순수함

≥99%

이름과 식별자

• 정식 스마일: CC(=O)OC1C(C(OC(C1OC(=O)C)OC2=C(C=C(C=C2)CO)N)C(=O)OC)OC(=O)C
• IUPAC Name: methyl (2S,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-[2-amino-4-(hydroxymethyl)phenoxy]oxane-2-carboxylate
• InChIKey: ZAZPQJAJSIUIEY-KVIJGQROSA-N
• INCHI: 1S/C20H25NO11/c1-9(23)28-15-16(29-10(2)24)18(30-11(3)25)20(32-17(15)19(26)27-4)31-14-6-5-12(8-22)7-13(14)21/h5-7,15-18,20,22H,8,21H2,1-4H3/t15-,16-,17-,18+,20+/m0/s1
• 이성체 SMILES: CC(=O)O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1OC(=O)C)OC2=C(C=C(C=C2)CO)N)C(=O)OC)OC(=O)C
• 분자량: 455.42

화학 및 물리적 특성

• 용해성: DMSO : 200 mg/mL (439.16 mM; Need ultrasonic)
• 감도: Moisture sensitive，Air sensitive，Heat sensitive
• 녹는점(°C): 138.0-142.0 °C
• 분자량: 455.400 g/mol
• XLogP3: -0.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 11
• Exact Mass: 455.143 Da
• Monoisotopic Mass: 455.143 Da
• Topological Polar Surface Area: 170.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 699.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 5
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 229977-57-5, the molecular formula is C20H25NO11, and the molecular weight is 455.42 g/mol. InChIKey ZAZPQJAJSIUIEY-KVIJGQROSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.