마페나이드 아세테이트 - ≥98% , Bacterial dihydropteroate synthase inhibitor, CAS No.13009-99-9, Bacterial dihydropteroate synthase inhibitor

CAS: 13009-99-9 Cat. No.: M123292 분자식: C₉H₁₄N₂O₄S 분자량: 246.28 EC 번호: 235-855-0

GRADE & PURITY ≥98%

Synonyms

FT-0630395 | 마페나이드 아세테이트(JAN/USP) | .ALPHA.-AMINO-P-톨루엔설포나미드 모노아세테이트 | 마페나이드(아세테이트) | 마페나이드 아세테이트(USP 모노그래프) | AM20050421 | SY107388 | HMS2231M06 | MAFENIDE 아세테이트(USP-RS) | BCP28537 | MAFENIDE ACETATE [MI] | NC00709

Storage

2-8°C에서 보관

Shipped In

젖은 얼음

개요

마페나이드 아세테이트는 설폰아미드 계열의 약물입니다.
항균

Specifications

동의어

FT-0630395 | 마페나이드 아세테이트(JAN/USP) | .ALPHA.-AMINO-P-톨루엔설포나미드 모노아세테이트 | 마페나이드(아세테이트) | 마페나이드 아세테이트(USP 모노그래프) | AM20050421 | SY107388 | HMS2231M06 | MAFENIDE 아세테이트(USP-RS) | BCP28537 | MAFENIDE ACETATE [MI] | NC00709

사양 및 순도

≥98%

생화학 및 생리적 메커니즘

마페니드는 그람 양성균, 그람 음성균 및 클로스트리디아에 대한 광범위한 활성을 가진 정균 항생제입니다. 마페나이드 아세테이트는 화상 상처의 진피층을 투과하여 세균이 많이 서식하는 것을 방지합니다.

보관 조건

2-8°C에서 보관

배송

젖은 얼음

작업 유형

INHIBITOR

작동 메커니즘

Bacterial dihydropteroate synthase inhibitor

순수함

≥98%

이름과 식별자

Pubchem Sid

508816772

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508816772

정식 스마일

CC(=O)O.C1=CC(=CC=C1CN)S(=O)(=O)N

IUPAC Name

acetic acid;4-(aminomethyl)benzenesulfonamide

InChIKey

UILOTUUZKGTYFQ-UHFFFAOYSA-N

INCHI

1S/C7H10N2O2S.C2H4O2/c8-5-6-1-3-7(4-2-6)12(9,10)11;1-2(3)4/h1-4H,5,8H2,(H2,9,10,11);1H3,(H,3,4)

이성체 SMILES

CC(=O)O.C1=CC(=CC=C1CN)S(=O)(=O)N

WGK 독일

3

분자량

246.28

Reaxy-Rn

4049145

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4049145&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • 분류 Carboxylic acids and derivatives
      • Subclass Carboxylic acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• 분류: Carboxylic acids and derivatives
• Subclass: Carboxylic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Carboxylic acids
• Alternative Parents: Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Not available
• Substituents: Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aromatic homomonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as carboxylic acids. These are compounds containing a carboxylic acid group with the formula -C(=O)OH.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)

Discover Target: ABCC2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCB11 Tchem Bile salt export pump (2311 Activities)

Discover Target: ABCB11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)

Discover Target: ABCC3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMN1 Tchem Survival motor neuron protein (34246 Activities)

Discover Target: SMN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

관련 대상(비인간)

Pseudomonas aeruginosa (123386 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Klebsiella pneumoniae (43867 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Acinetobacter baumannii (41033 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cryptococcus neoformans (21258 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida albicans (78123 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TGR Thioredoxin glutathione reductase (28579 Activities)

Discover Target: TGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 용해성: Soluble in Methanol and Water
• 분자량: 246.290 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 246.067 Da
• Monoisotopic Mass: 246.067 Da
• Topological Polar Surface Area: 132.000 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 255.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3