Magnolol - 10mM in DMSO , CAS No.528-43-8

CAS: 528-43-8 Cat. No.: M407956 분자식: C₁₈H₁₈O₂ 분자량: 266.33 Beilstein Registry Number: 6(4)6918 EC 번호: 610-903-7

GRADE & PURITY 10mM in DMSO

Synonyms

NSC 293099 | [1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propen-1-yl-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Magnolol Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.
In vitro

Magnolol is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. Magnolol preferentially increases (3)H-muscimol binding to hippocampus compared to cortex and cerebellum in vitro. Magnolol has a more potent enhancing effect on GABA_A receptor alpha2 subunit. Magnolol shows significant inhibitory activities against Trichophyton mentagrophytes, Microsporium gypseum, Epidermophyton floccosum, Aspergillus niger, Cryptococcus neoformans, and Candida albicans with minimum inhibitory concentrations (MIC) in a range of 25-100 μg/ml.

In vivo

LD50: Mice 2200mg/kg (i.g.).
Cell Data

cell lines：LNCaP/AR prostate cancer cell line

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

동의어

NSC 293099 | [1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propen-1-yl-

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

Magnolol (NSC 293099) is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties. It can block TNF-α-induced NF-KB activation.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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이름과 식별자

이성체 SMILES

C=CCC1=CC(=C(C=C1)O)C2=C(C=CC(=C2)CC=C)O

WGK 독일

3

RTECS

DV5105500

UN 번호

3077

분자량

266.33

Beilstein

6(4)6918

Reaxy-Rn

1982224

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1982224&ln=

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 100 mg/mL (148.9 mM); Ethanol: 4 mg/mL (5.95 mM); Water: Insoluble
• 끓는점(°C): 180 °C/1 mmHg
• 녹는점(°C): 101 °C

자주 묻는 질문

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 528-43-8, the molecular formula is C18H18O2, and the molecular weight is 266.33 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.