Mal-PEG2-Val-Cit-PAB-OH - ≥95% , CAS No.2055041-38-6

CAS: 2055041-38-6 Cat. No.: M596148 분자식: C₂₉H₄₂N₆O₉ 분자량: 618.7

GRADE & PURITY ≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The maleimide group is reactive toward thiol groups between pH 6.5 to 7.5. The hydroxyl group can be reacted to further derivatize the compound. The hydrophobic PEG chain increases the water solubility of the compound.

Specifications

사양 및 순도

≥95%

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥95%

이름과 식별자

분자량

618.7

화학 및 물리적 특성

• 용해성: Solubility in DMSO, DMF

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2055041-38-6, the molecular formula is C29H42N6O9, and the molecular weight is 618.7 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.