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· · COA & SDS 모든 제품에 대한 사용 가능 · 주식 상품에 대한 같은 날 배송 홈 목표 / 경로 / 질병에 따라 신호 전달 경로를 통해 자가포식 자가포식 Memantine Hydrochloride - ≥98% , Glutamate [NMDA] receptor negative allosteric modulator, CAS No.41100-52-1, Glutamate [NMDA] receptor negative allosteric modulator Memantine Hydrochloride - ≥98% , Glutamate [NMDA] receptor negative allosteric modulator, CAS No.41100-52-1, Glutamate [NMDA] receptor negative allosteric modulator
Synonyms
MEMANTINE HYDROCHLORIDE (USP-RS) | Memantine Accord | NMI-131 | 3,5-dimethyladamantan-1-amine;hydrochloride | Axura | EINECS 255-219-6 | NCGC00262963-01 | 3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine hydrochloride | AMY40819 | SMR000875213 | MLS0013326
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요 Memantine hydrochloride has been used:
· as a media supplement to serve as a control to study the neuroprotective effects of erythropoietin in N-methyl-D-aspartate receptor-induced toxicity
· to intraperitoneally inject experimental animal to study its effect on traumatic injury
· as a test compound to determine the dynamic range and selectivity of retinal pigment epithelium tissue penetration
Specifications 동의어
MEMANTINE HYDROCHLORIDE (USP-RS) | Memantine Accord | NMI-131 | 3,5-dimethyladamantan-1-amine;hydrochloride | Axura | EINECS 255-219-6 | NCGC00262963-01 | 3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine hydrochloride | AMY40819 | SMR000875213 | MLS0013326
생화학 및 생리적 메커니즘
Memantine is effective against Alzheimer′s disease and Parkinson′s disease. It is also useful in treating epilepsy, motor neurone disease and trauma.Antagonist at the NMDA receptor. Acts as a fast, voltage-dependent, open channel NMDA receptor blocker. Us
작업 유형
NEGATIVE ALLOSTERIC MODULATOR
작동 메커니즘
Glutamate [NMDA] receptor negative allosteric modulator
참고
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
이름과 식별자 Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/488188516
정식 스마일
CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
IUPAC Name
3,5-dimethyladamantan-1-amine;hydrochloride
InChIKey
LDDHMLJTFXJGPI-UHFFFAOYSA-N
INCHI
1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H
이성체 SMILES
CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6573843&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic nitrogen compounds 분류 Organonitrogen compounds Subclass Amines Intermediate Tree Nodes Primary amines Direct Parent Monoalkylamines Alternative Parents Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives Molecular Framework Aliphatic homopolycyclic compounds Substituents Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Primary aliphatic amine - Aliphatic homopolycyclic compound 설명 This compound belongs to the class of organic compounds known as monoalkylamines. These are organic compounds containing an primary aliphatic amine group. External Descriptors hydrochloride Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 용해성 Soluble in water 녹는점(°C) 292°C 분자량 215.760 g/mol XLogP3 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 1 Rotatable Bond Count 0 Exact Mass 215.144 Da Monoisotopic Mass 215.144 Da Topological Polar Surface Area 26.000 Ų Heavy Atom Count 14 Formal Charge 0 Complexity 240.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 2 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
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