Menthone - 10mM in DMSO , CAS No.10458-14-7

CAS: 10458-14-7 Cat. No.: M420453 분자식: C₁₀H₁₈O 분자량: 154.25 Beilstein Registry Number: 774527 EC 번호: 233-944-9

GRADE & PURITY 10mM in DMSO

Synonyms

AKOS000121372 | NSC 113134 | a menthone | MFCD00062998 | p-Menthan-3-one, (1R,4R)-(+)- | 5-methyl-2-propan-2-ylcyclohexan-1-one | CHEBI:36503 | FT-0693859 | Menthone, analytical standard | 2-Isopropyl-5-methylcyclohexanone | trans-5-methyl-2-(1-methylethy

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Menthone is a cyclic oxygenated terpene and its antioxidant potential has been evaluated.It is one of the key active component of Danshu capsule (DSC), a medicinal compound in traditional Chinese medicine.

Menthone has been used in the following studies:

· To prepare the model flavor mix in a study to investigate the release of various aroma compounds in xanthan-thickened food model systems having different viscosities. 

· As standard in the quantification of volatile constituents and odour-activity value (OAV) in ′Marion′ and ′Black Diamond′.

· Modified semisolid agar antifungal susceptibility method (SAAS) to investigate the anti-fungal activities of various cyclic terpenes against Fusarium verticillioides MRC 826.

Specifications

동의어

AKOS000121372 | NSC 113134 | a menthone | MFCD00062998 | p-Menthan-3-one, (1R,4R)-(+)- | 5-methyl-2-propan-2-ylcyclohexan-1-one | CHEBI:36503 | FT-0693859 | Menthone, analytical standard | 2-Isopropyl-5-methylcyclohexanone | trans-5-methyl-2-(1-methylethy

사양 및 순도

10mM in DMSO

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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이름과 식별자

• Pubchem Sid: 528775596
• 정식 스마일: CC1CCC(C(=O)C1)C(C)C
• IUPAC Name: 5-methyl-2-propan-2-ylcyclohexan-1-one
• InChIKey: NFLGAXVYCFJBMK-UHFFFAOYSA-N
• INCHI: 1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3
• 이성체 SMILES: CC1CCC(C(=O)C1)C(C)C
• WGK 독일: 3
• 분자량: 154.25
• Beilstein: 774527
• Reaxy-Rn: 774527
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=774527&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • 분류 Prenol lipids
      • Subclass Monoterpenoids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• 분류: Prenol lipids
• Subclass: Monoterpenoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Menthane monoterpenoids
• Alternative Parents: Monocyclic monoterpenoids Cyclic ketones Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: P-menthane monoterpenoid - Monocyclic monoterpenoid - Cyclic ketone - Ketone - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic homomonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as menthane monoterpenoids. These are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes.
• External Descriptors: a menthone

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(비인간)

GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 발화점(°C): 72℃
• 끓는점(°C): 85-88 °C/12 mmHg
• 분자량: 154.250 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 154.136 Da
• Monoisotopic Mass: 154.136 Da
• Topological Polar Surface Area: 17.100 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 149.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

참고 문헌

1. Wenming Zhao, Chengwei Yang, Ning Zhang, Yuanyuan Peng, Ying Ma, Keru Gu, Xia Liu, Xiaohui Liu, Xijian Liu, Yumin Liu, Songkai Li, Linjing Zhao.  (2023)  Menthone Exerts its Antimicrobial Activity Against Methicillin Resistant Staphylococcus aureus by Affecting Cell Membrane Properties and Lipid Profile.  Drug Design Development and Therapy,      [PMID:36721663] [10.2147/DDDT.S384716]

2. Xuan Ji, Jing Du, Jiaying Gu, Jie Yang, Li Cheng, Zhaofeng Li, Caiming Li, Yan Hong.  (2022)  Structure and Menthone Encapsulation of Corn Starch Modified by Octenyl Succinic Anhydride and Enzymatic Treatment.  JOURNAL OF FOOD QUALITY,      [PMID:] [10.1155/2022/4556827]

3. Changyue Deng, Chuan Cao, Yingying Zhang, Jingwei Hu, Yongqiang Gong, Mingming Zheng, Yibin Zhou.  (2021)  Formation and stabilization mechanism of β-cyclodextrin inclusion complex with C10 aroma molecules.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2021.107013]

4. Ying Zhang, Tao Zhang, Xinhang Wang, Zhipeng Bian, Xiaofang Zhang, Guoqing Yang, Yanhui Lu.  (2024)  Volatiles from essential oils of three Lamiaceae plants repel the winged cotton aphid, disturb its feeding behavior and reduce its fecundity.  PEST MANAGEMENT SCIENCE,  80  (9): (4253-4263).  [PMID:38624184] [10.1002/ps.8130]

5. Hamza Tariq, Peiyu Chen, Gang Wang, Siyuan Xie, Lanning Wang, Jingkun Lv, Fei Wang, Muhammad Saqib Bilal, Abdur Rashid Khan, Nasir Ahmed Rajput, Danyu Shen, Daolong Dou.  (2025)  Trans-2-decenal inhibits Alternaria alternata through disruption of redox homeostasis and membrane integrity.  PEST MANAGEMENT SCIENCE,      [PMID:40948311] [10.1002/ps.70223]

6. Bo Sui, Yuxin Wang, Shanshan Ma, Shihao Sun, Hui Xi, Dingzhong Wang, Shusheng Zhang, Hongtu Zhang, Wuduo Zhao.  (2025)  Synergistic Ionization via Plasma-Droplet Coupling in an LTP-DESI Hybrid Source for Sensitive Analysis of Volatile Aroma Compounds.  ANALYTICAL CHEMISTRY,      [PMID:41171106] [10.1021/acs.analchem.5c04362]