Methscopolamine - 10mM in DMSO , Muscarinic acetylcholine receptor M1 antagonist, CAS No.155-41-9, Muscarinic acetylcholine receptor M1 antagonist

CAS: 155-41-9 Cat. No.: M408775 분자식: C18H24BrNO4 분자량: 398.29 EC 번호: 205-844-5 PubChem CID: 5459110
주문 가능
GRADE & PURITY 10mM in DMSO
Synonyms
(1α,​2β,​4β,​5α,​7β)​-7-​[(2S)​-​3-​hydroxy-​1-​oxo-​2-​phenylpropoxy]​-​9,​9-​dimethyl-3-​oxa-​9-​azoniatricyclo[3.3.1​.02,​4]​nonane, bromide (1:1)​
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
USA
독일 (EU)*
Price
Qty
1ml
M408775-1ml
1 재고 있음
US$42.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

Methscopolamine is a muscarinic acetylcholine receptor blocker.
In vitro


In vivo


Cell Data

cell lines:A375, 22RV1 and T474 cells

Concentrations:

Incubation Time:

Powder Purity:≥95%

Specifications

동의어
(1α,​2β,​4β,​5α,​7β)​-7-​[(2S)​-​3-​hydroxy-​1-​oxo-​2-​phenylpropoxy]​-​9,​9-​dimethyl-3-​oxa-​9-​azoniatricyclo[3.3.1​.02,​4]​nonane, bromide (1:1)​
사양 및 순도
10mM in DMSO
생화학 및 생리적 메커니즘
Methscopolamine is a muscarinic acetylcholine receptor blocker.
보관 조건
Store at -80°C
배송
Dry ice packs + Cold packs
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
작업 유형
ANTAGONIST
작동 메커니즘
Muscarinic acetylcholine receptor M1 antagonist
이름과 식별자
이성체 SMILES C[N+]1([C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4)C.[Br-]
PubChem CID 5459110
분자량 398.29

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
용해성Solubility (25°C) In vitro DMSO: 30 mg/mL (100.21 mM); Water: Insoluble; Ethanol: Insoluble;
특정 회전[α]-24°C
Citations of This Product
참고 문헌
1. Song Changgeng, Zhao Yan, Zhang Jiajia, Dong Ziyi, Kang Xin, Pan Yuqi, Du Jinle, Gao Yiting, Zhang Haifeng, Xi Ye, Ding Hui, Kuang Fang, Wang Wenting, Luo Ceng, Zhang Zhengping, Zhao Qinpeng, Yang Jiazhou, Jiang Wen, Wu Shengxi, Gao Fang.  (2023)  Spatial Distribution of Parvalbumin-Positive Fibers in the Mouse Brain and Their Alterations in Mouse Models of Temporal Lobe Epilepsy and Parkinson’s Disease.  Neuroscience Bulletin,      [PMID:37523099] [10.1007/s12264-023-01083-0]
2. Song Changgeng, Zhao Jingjing, Hao Jianmin, Mi Dan, Zhang Jiajia, Liu Yingying, Wu Shengxi, Gao Fang, Jiang Wen.  (2023)  Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus.  Cell Death Discovery,  (1): (1-18).  [PMID:37142587] [10.1038/s41420-023-01445-7]
3. Fankai Gao, Rui Chen, Shuo Li, An Li, Bo Bai, Rulin Mi, Guofang Xue.  (2023)  (+)-Borneol exerts neuroprotective effects via suppressing the NF-κB pathway in the pilocarpine-induced epileptogenesis rat model.  BRAIN RESEARCH,      [PMID:37127175] [10.1016/j.brainres.2023.148382]
4. Huijie Huangfu, Xugeng Guo, Ning Li, Ye Xiong, Yafei Huang, Jinglai Zhang, Li Wang.  (2023)  A smart composite coating with self-reporting and self-healing functions to enhance corrosion protection for magnesium alloys.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2023.107598]
5. Dai Jie, Shen Hai-lin, Li Jia, Zhou Yong, Dong Zheng-xie, Zhu Xiang-yang.  (2024)  Gastrodin Attenuates Neuroinflammation and Injury in Young Rats with LiCl/Pilocarpine-Induced Status Epilepticus.  BIOCHEMICAL GENETICS,      [PMID:39570508] [10.1007/s10528-024-10971-7]
6. Yang Yu, Li Xingchang, Gong Shuxian, Sui Lisen, Liu Jian, Yu Fangjun, Zhang Tianpeng.  (2025)  E4BP4-Driven Circadian SLC6A1 Expression Governs Tiagabine Chronoefficacy in Temporal Lobe Epilepsy.  MOLECULAR NEUROBIOLOGY,  63  (1): (242).  [PMID:41335220] [10.1007/s12035-025-05498-w]
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