Miconazole - Moligand™, 10mM in DMSO , Cytochrome P450 51 inhibitor, CAS No.22916-47-8, Cytochrome P450 51 inhibitor

CAS: 22916-47-8 Cat. No.: M407984 분자식: C18H14Cl4N2O 분자량: 416.14 EC 번호: 245-324-5
주문 가능
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
1-​[2-​(2,​4-​dichlorophenyl)​-​2-​[(2,​4-​dichlorophenyl)​methoxy]​ethyl]​-1H-​imidazole
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
USA
독일 (EU)*
Price
Qty
1ml
M407984-1ml
2 재고 있음
—

US$68.90

US$99.90
저장 US$31.00 (31.03%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

Miconazole Miconazole (Monistat) is an imidazole antifungal agent.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥96%

Specifications

동의어
1-​[2-​(2,​4-​dichlorophenyl)​-​2-​[(2,​4-​dichlorophenyl)​methoxy]​ethyl]​-1H-​imidazole
사양 및 순도
Moligand™, 10mM in DMSO
생화학 및 생리적 메커니즘
Miconazole (Monistat) is an imidazole antifungal agent.
보관 조건
Store at -80°C
배송
Dry ice packs + Cold packs
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
등급
Moligand™
작업 유형
CHANNEL BLOCKER, INHIBITOR
작동 메커니즘
Cytochrome P450 51 inhibitor
제품 특성
ALogP5.3
이름과 식별자
이성체 SMILES C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl
분자량 416.14
Reaxy-Rn 965511
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=965511&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

관련 대상(인간)
CYP2D6 Tclin Cytochrome P450 2D6 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2J2 Tchem Cytochrome P450 2J2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2C19 Tchem Cytochrome P450 2C19 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP3A4 Tclin Cytochrome P450 3A4 (6 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP51A1 Tchem Lanosterol 14-alpha demethylase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP2C9 Tchem Cytochrome P450 2C9 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A4 Tclin Sodium-dependent serotonin transporter (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TBXAS1 Tchem Thromboxane-A synthase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP19A1 Tclin Aromatase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP17A1 Tclin Steroid 17-alpha-hydroxylase/17,20 lyase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
용해성Solubility (25°C) In vitro DMSO: 30 mg/mL (46.11 mM); Water: Insoluble; Ethanol: Insoluble;
녹는점(°C)83-97°C
자주 묻는 질문과 기사
Citations of This Product
참고 문헌
1. Xu Yang-ding, Guo Yu-jie, Mao He-rong, Xiong Zhi-xiang, Luo Meng-yu, Luo Rui-qi, Lu Shan, Huang Lu, Hong Yi.  (2023)  Integration of transcriptomics and proteomics to elucidate inhibitory effect and mechanism of rosmarinic acid from Perilla frutescens (L.) Britt. in treating Trichophyton mentagrophytes.  Chinese Medicine,  18  (1): (1-20).  [PMID:37280712] [10.1186/s13020-023-00772-2]
2. Kamran Bashir, Zhimin Luo, Guoning Chen, Hua Shu, Xia Cui, Wen Li, Wang Lu, Qiang Fu.  (2019)  Development of Surface Molecularly Imprinted Polymers as Dispersive Solid Phase Extraction Coupled with HPLC Method for the Removal and Detection of Griseofulvin in Surface Water.  International Journal of Environmental Research and Public Health,  17  (1): (134).  [PMID:31878121] [10.3390/ijerph17010134]
솔루션 계산기
리뷰

고객 리뷰

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.