MitoMark Red I - ≥90%(HPLC) , CAS No.167095-09-2

CAS: 167095-09-2 Cat. No.: M287728 분자식: C₃₂H₃₂Cl₂N₂O 분자량: 531.52

GRADE & PURITY ≥90%(HPLC)

Synonyms

9-[4-(chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-4-ium chloride | chloromethyl-X-rosamine | 9-[4-(Chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xanthe

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

개요

MitoSceneTM Red CMXRos is a red fluorescent dye that contains chloromethyl functional groups that label mitochondria. MitoSceneTM Red CMXRos is passively transported across the cell membrane and directly accumulates on the active mitochondria after simple incubation with living cells. The accumulation of the dye depends on the membrane potential. Once the mitochondria have been stained, they can also be fixed with an aldehyde fixative as required by subsequent experiments. For immunohistochemical and in situ hybridization experiments, the cells need to be permeated first, and MitoSceneTM Red CMXRos can also stain the mitochondria of the cells. The dye is suitable for double labeling experiments, and its red fluorescence can be well distinguished from other green fluorescence probes LumiTracker Mito Red CMXRos is a cationic, red-fluorescent dye for staining active mitochondria in live cells. CMXRos is a hydrophobic compound that passively diffuses across the plasma membrane and selectively accumulates in active mitochondria based on their membrane potential. LumiTracker Mito Red CMXRos is compatible with aldehyde fixation. This dye is useful to indicate cell health as well as for mitochondria localization.

Specifications

동의어

9-[4-(chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-4-ium chloride | chloromethyl-X-rosamine | 9-[4-(Chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xanthe

사양 및 순도

≥90%(HPLC)

생화학 및 생리적 메커니즘

Red fluorescent mitochondrial stain. Fluorescence intensity is dependent on mitochondrial membrane potential. Excitation/emission maxima λ ~ 578/599 nm.

보관 조건

Protected from light,Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥90%(HPLC)

이름과 식별자

정식 스마일

C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=CC=C(C=C8)CCl)CCC7.[Cl-]

IUPAC Name

16-[4-(chloromethyl)phenyl]-3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaene;chloride

InChIKey

IKEOZQLIVHGQLJ-UHFFFAOYSA-M

INCHI

1S/C32H32ClN2O.ClH/c33-19-20-9-11-21(12-10-20)28-26-17-22-5-1-13-34-15-3-7-24(29(22)34)31(26)36-32-25-8-4-16-35-14-2-6-23(30(25)35)18-27(28)32;/h9-12,17-18H,1-8,13-16,19H2;1H/q+1;/p-1

이성체 SMILES

C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=CC=C(C=C8)CCl)CCC7.[Cl-]

분자량

531.52

Reaxy-Rn

14504784

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14504784&ln=

화학 및 물리적 특성

• 용해성: Solvent:DMSO, Max Conc. mg/mL: 0.53, Max Conc. mM: 1
• 감도: Moisture Sensitive，Light Sensitive