MK-0159 - ≥99% , CAS No.2641484-61-7

CAS: 2641484-61-7 Cat. No.: M648927 분자식: C₂₀H₂₄N₄O₃S 분자량: 400.49

등급 & 순도 ≥99%

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

개요

MK-0159 (compound 37) is an orally active, potent and selective CD38 inhibitor, with IC 50 values of 22, 3, and 70 nM for human, mouse and rat CD38 , respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD + (nicotinamide adenine dinucleotide) and reduces ADPR (adenosine diphosphate ribose) in whole blood and heart

Form:Solid

IC50& Target:IC 50 : 3 nM (mouse CD38), 22 ± 5 nM (hCD38), 70 nM (rat CD38)

사양

사양 및 순도

≥99%

생화학 및 생리적 메커니즘

MK-0159 (compound 37) is an orally active, potent and selective CD38 inhibitor, with IC 50 values of 22, 3, and 70 nM for human, mouse and rat CD38 , respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159

보관 조건

Store at 2-8°C,Protected from light,Desiccated

배송

Wet ice

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작업 유형

INHIBITOR

순수함

≥99%

이름과 식별자

분자량

400.49

화학 및 물리적 특성

• 용해성: DMSO : 100 mg/mL (249.69 mM; Need ultrasonic)

자주 묻는 질문

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