MK 0677 - 10mM in DMSO , Ghrelin receptor agonist, CAS No.159752-10-0, Ghrelin receptor agonist

Name: MK 0677 - 10mM in DMSO , Ghrelin receptor agonist, CAS No.159752-10-0, Ghrelin receptor agonist
SKU: M580439
Availability: InStock

CAS: 159752-10-0 Cat. No.: M580439 분자식: C₂₈H₄₀N₄O₈S₂ 분자량: 624.77 PubChem CID: 6450830

COA

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MK 0677 - 10mM in DMSO CAS No(159752-10-0) by Aladdin Scientific

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주문 가능

GRADE & PURITY 10mM in DMSO

Synonyms

2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide;methanesulfonic acid | 2-Amino-N-{3-(benzyloxy)-1-[1-(methanesulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidin]-1'-yl]-1-oxopro

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications 이름과 식별자 Documentation Advanced Data Taxonomic Classification 3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 솔루션 계산기 리뷰 자주 묻는 질문

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

동의어

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

High affinity ghrelin receptor agonist (pKi= 8.14). Growth hormone (GH) secretagog; stimulates GH release from rat pituitary cellsin vitro(EC50= 1.3 nM) and enhances GH plasma levelsin vivo. Also attenuatesisoproterenol-induced lipolysis in rat adipocytes

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

AGONIST

작동 메커니즘

Ghrelin receptor agonist

이름과 식별자

정식 스마일

CC(C)(C(=O)NC(COCC1=CC=CC=C1)C(=O)N2CCC3(CC2)CN(C4=CC=CC=C34)S(=O)(=O)C)N.CS(=O)(=O)O

IUPAC Name

2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide;methanesulfonic acid

InChIKey

DUGMCDWNXXFHDE-VZYDHVRKSA-N

INCHI

1S/C27H36N4O5S.CH4O3S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27;1-5(2,3)4/h4-12,22H,13-19,28H2,1-3H3,(H,29,33);1H3,(H,2,3,4)/t22-;/m1./s1

이성체 SMILES

CC(C)(C(=O)N[C@H](COCC1=CC=CC=C1)C(=O)N2CCC3(CC2)CN(C4=CC=CC=C34)S(=O)(=O)C)N.CS(=O)(=O)O

PubChem CID

6450830

분자량

624.77

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - 분류 Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Peptides
        Level6 Dipeptides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
분류	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Peptides
Direct Parent	Dipeptides
Alternative Parents	N-acyl-alpha amino acids and derivatives Alpha amino acid amides N-acylpiperidines Indoles and derivatives Benzylethers Organosulfonamides Organic sulfonamides Tertiary carboxylic acid amides Sulfonyls Organosulfonic acids Alkanesulfonic acids Methanesulfonates Secondary carboxylic acid amides Azacyclic compounds Dialkyl ethers Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides
Molecular Framework	Not available
Substituents	Alpha-dipeptide - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Alpha-amino acid or derivatives - Benzylether - Indole or derivatives - N-acyl-piperidine - Monocyclic benzene moiety - Benzenoid - Piperidine - Organic sulfonic acid amide - Organosulfonic acid amide - Methanesulfonate - Alkanesulfonic acid - Tertiary carboxylic acid amide - Organic sulfonic acid or derivatives - Sulfonyl - Organosulfonic acid or derivatives - Organosulfonic acid - Amino acid or derivatives - Secondary carboxylic acid amide - Carboxamide group - Dialkyl ether - Ether - Azacycle - Organoheterocyclic compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Carbonyl group - Amine - Primary amine - Organooxygen compound - Organic nitrogen compound - Primary aliphatic amine - Organosulfur compound - Organic oxygen compound - Aromatic heteropolycyclic compound
설명	This compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

용해성	Solvent:water, Max Conc. mg/mL: 31.24, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 62.48, Max Conc. mM: 100
감도	Moisture & heat sensitive
분자량	624.800 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	8
Exact Mass	624.229 Da
Monoisotopic Mass	624.229 Da
Topological Polar Surface Area	193.000 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	1010.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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리뷰

자주 묻는 질문

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 159752-10-0, the molecular formula is C28H40N4O8S2, and the molecular weight is 624.77 g/mol. InChIKey DUGMCDWNXXFHDE-VZYDHVRKSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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