ML 10302 - Moligand™,≥98% , Agonist of 5-HT 4 receptor, CAS No.148868-55-7, Agonist of 5-HT 4 receptor

CAS: 148868-55-7 Cat. No.: M611931 분자식: C15H21ClN2O3 분자량: 312.79 PubChem CID: 5311299
주문 가능
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
Benzoic acid, 4-amino-5-chloro-2-methoxy-, 2-(1-piperidinyl)ethyl ester | SCHEMBL2579561 | NCGC00094130-01 | 2-(piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate | J-008526 | LP00795 | GTPL235 | L000650 | HY-14441 | 2-piperidin-1-ylethyl 4-amino-5-c
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
독일 (EU)*
Price
Qty
1mg
M611931-1mg
주문제작 · 8~12주
US$79.90
5mg
M611931-5mg
주문제작 · 8~12주
US$189.90
10mg
M611931-10mg
주문제작 · 8~12주
US$259.90
25mg
M611931-25mg
주문제작 · 8~12주
US$459.90
50mg
M611931-50mg
주문제작 · 8~12주
US$639.90
100mg
M611931-100mg
주문제작 · 8~12주
US$899.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

ML 10302 is a potent agonist 5-HT4 receptor with Ki of 1.07 nM. 5-Hydroxytryptamine (5-HT4) receptor agonists stimulate gut motility through cholinergic pathways. ML10302 induces significant prokinesia both in the small bowel and colon through activation of cholinergic pathways. ML 10302 also has the potential for the research of neurology diseases.

Specifications

동의어
Benzoic acid, 4-amino-5-chloro-2-methoxy-, 2-(1-piperidinyl)ethyl ester | SCHEMBL2579561 | NCGC00094130-01 | 2-(piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate | J-008526 | LP00795 | GTPL235 | L000650 | HY-14441 | 2-piperidin-1-ylethyl 4-amino-5-c
사양 및 순도
Moligand™,≥98%
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
등급
Moligand™
작업 유형
AGONIST
작동 메커니즘
Agonist of 5-HT 4 receptor
순수함
≥98%
이름과 식별자
정식 스마일COC1=CC(=C(C=C1C(=O)OCCN2CCCCC2)Cl)N
IUPAC Name2-piperidin-1-ylethyl 4-amino-5-chloro-2-methoxybenzoate
InChIKeyRVFIAQAAZUEPPE-UHFFFAOYSA-N
INCHI1S/C15H21ClN2O3/c1-20-14-10-13(17)12(16)9-11(14)15(19)21-8-7-18-5-3-2-4-6-18/h9-10H,2-8,17H2,1H3
이성체 SMILES COC1=CC(=C(C=C1C(=O)OCCN2CCCCC2)Cl)N
WGK 독일 3
PubChem CID 5311299
분자량 312.79

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
분류Benzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Methoxybenzoic acids and derivatives
Direct ParentO-methoxybenzoic acids and derivatives
Alternative Parents 3-halobenzoic acids and derivatives  Aminobenzoic acids and derivatives  Benzoic acid esters  Aminophenyl ethers  Methoxyanilines  Phenoxy compounds  Methoxybenzenes  Anisoles  Benzoyl derivatives  Alkyl aryl ethers  Chlorobenzenes  Piperidines  Aryl chlorides  Trialkylamines  Amino acids and derivatives  Carboxylic acid esters  Azacyclic compounds  Organic oxides  Organochlorides  Hydrocarbon derivatives  Primary amines  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents O-methoxybenzoic acid or derivatives - Aminobenzoic acid or derivatives - Benzoate ester - 3-halobenzoic acid or derivatives - Halobenzoic acid or derivatives - Aminophenyl ether - Methoxyaniline - Anisole - Phenoxy compound - Benzoyl - Phenol ether - Aniline or substituted anilines - Methoxybenzene - Alkyl aryl ether - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Piperidine - Tertiary aliphatic amine - Amino acid or derivatives - Carboxylic acid ester - Tertiary amine - Organoheterocyclic compound - Azacycle - Carboxylic acid derivative - Ether - Organooxygen compound - Organochloride - Amine - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Organohalogen compound - Organic oxygen compound - Organonitrogen compound - Primary amine - Aromatic heteromonocyclic compound
설명This compound belongs to the class of organic compounds known as o-methoxybenzoic acids and derivatives. These are benzoic acids in which the hydrogen atom at position 2 of the benzene ring is replaced by a methoxy group.
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





관련 대상(인간)
HTR4 Tclin 5-hydroxytryptamine receptor 4 (14 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLA Tclin Alpha-galactosidase A (5444 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MPHOSPH8 Tbio M-phase phosphoprotein 8 (656 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
관련 대상(비인간)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
nfo Endonuclease 4 (425 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGAM 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (46 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Htr3a Serotonin 3 (5-HT3) receptor (1834 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
분자량312.790 g/mol
XLogP32.600
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass312.124 Da
Monoisotopic Mass312.124 Da
Topological Polar Surface Area64.800 Ų
Heavy Atom Count21
Formal Charge0
Complexity337.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
솔루션 계산기
리뷰

고객 리뷰

자주 묻는 질문

What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 148868-55-7, the molecular formula is C15H21ClN2O3, and the molecular weight is 312.79 g/mol. InChIKey RVFIAQAAZUEPPE-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.