🧪

Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Cell permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Catalyzes the dismutation of O2- even in the presence of excess EDTA. Displays a protective effect against H2O2 mediated injury in astroglial cells.

Specifications

동의어

4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide | SCHEMBL8218 | L01XE05 | NSC7177 | UNII-9ZOQ3TZI87 | NSC747971 | NSC-747971 | BAY 439006 | BAY 43-9006 | 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]ca

사양 및 순도

≥95%

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

순수함

≥95%

이름과 식별자

Pubchem Sid

488188634

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488188634

정식 스마일

CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F

IUPAC Name

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide

InChIKey

MLDQJTXFUGDVEO-UHFFFAOYSA-N

INCHI

1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)

이성체 SMILES

CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F

분자량

909

Reaxy-Rn

9666200

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9666200&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - 분류 Organooxygen compounds
    - Subclass Ethers

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
분류	Organooxygen compounds
Subclass	Ethers
Intermediate Tree Nodes	Not available
Direct Parent	Diarylethers
Alternative Parents	Trifluoromethylbenzenes N-phenylureas Pyridinecarboxamides Phenoxy compounds Phenol ethers 2-heteroaryl carboxamides Chlorobenzenes Aryl chlorides Heteroaromatic compounds Ureas Secondary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organofluorides Organochlorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Diaryl ether - Trifluoromethylbenzene - N-phenylurea - Pyridine carboxylic acid or derivatives - Pyridinecarboxamide - 2-heteroaryl carboxamide - Phenoxy compound - Phenol ether - Halobenzene - Chlorobenzene - Benzenoid - Pyridine - Monocyclic benzene moiety - Aryl halide - Aryl chloride - Heteroaromatic compound - Urea - Secondary carboxylic acid amide - Carbonic acid derivative - Carboxamide group - Azacycle - Organoheterocyclic compound - Carboxylic acid derivative - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Organofluoride - Organochloride - Organohalogen compound - Carbonyl group - Alkyl halide - Alkyl fluoride - Aromatic heteromonocyclic compound
설명	This compound belongs to the class of organic compounds known as diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups.
External Descriptors	aromatic ether - ureas - monochlorobenzenes - (trifluoromethyl)benzenes - pyridinecarboxamide
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

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리뷰

Application Protocols

No item-specific validated protocols are provided. The following generic, literature-based procedures illustrate common laboratory uses of MnTMPyP complexes. Adjust to your system and consult primary references.

A. Preparing stock solutions

Dissolve MnTMPyP pentachloride in ultrapure water to 1–10 mM. Gently vortex to dissolve completely. Protect from light. Filter if needed (0.22 μm PTFE or PES). Determine concentration by UV–Vis using appropriate extinction coefficient for your buffer.

B. Cell-free SOD-mimetic assay (WST-1 method)

Buffer: 50 mM phosphate, 100 mM NaCl, pH 7.4. Add xanthine/xanthine oxidase to generate O2•−, WST-1 as the indicator. Add serial dilutions of MnTMPyP. Monitor absorbance increase of WST-1 formazan at 440–450 nm; calculate activity as inhibition relative to no-catalyst control. Include controls for background autoxidation.

C. Peroxidase-like ABTS oxidation

Buffer: 50 mM acetate, pH 5.5. Add ABTS (0.5–2 mM) and H2O2 (0.1–2 mM) with μM MnTMPyP. Follow formation of ABTS•+ at 414 nm. Optimize H2O2 to avoid catalyst bleaching.

D. Oxidative epoxidation (analytical scale)

Substrate: styrene (10 mM) in water–acetonitrile (1:1). Add MnTMPyP (0.5 mol%). Initiate with NaClO (pH ~9, slow addition at 0–5°C). Monitor by GC or HPLC. Quench with sodium thiosulfate and neutralize.

These outlines are for research use only and require risk assessment, method validation, and appropriate controls.

Biological Roles

Research context (literature; not product specifications or medical claims):

Reactive oxygen/nitrogen species (ROS/RNS): MnTMPyP complexes are widely used as catalytic mimics of superoxide dismutase (SOD) in cell-free systems, promoting disproportionation of O2•− via Mn(III)/Mn(II) cycling. They can also interact with peroxynitrite and hydrogen peroxide, serving as tools to modulate and probe oxidative chemistry in vitro.
Charge-driven interactions: The tetracationic periphery favors electrostatic association with nucleic acids, membranes, and acidic proteins. This property is exploited in biophysical experiments to study binding, energy transfer, and electron transfer.
Spectroscopic marker: Intense Soret and Q-band absorptions provide convenient optical handles for tracking localization and environment-dependent spectral shifts in model systems.
Enzyme-mimetic catalysis: Beyond SOD-like activity, manganese porphyrins can exhibit catalase- or peroxidase-like behaviors depending on axial ligation, pH, and substrate availability, enabling mechanistic studies of redox enzymes using simplified small-molecule mimics.

Notes and caveats:

Speciation matters: pH, ionic strength (especially Cl−), and coordinating ligands (e.g., imidazole, phosphate) affect axial ligation and catalytic behavior; define and report buffer composition in biological assays.
Protein interactions: Strong electrostatics may lead to nonspecific binding and altered apparent activity; include controls (ionic strength titrations, inert salts).
All uses are for research only; not for diagnostic or therapeutic applications.

Buffer Applications

MnTMPyP pentachloride is commonly prepared and used in aqueous buffers for redox and biophysical studies. No item-specific buffer recipe is provided here; the following are general, literature-based practices for handling cationic manganese porphyrins.

Typical buffers: phosphate (10–50 mM), HEPES, or Tris at pH 6.8–7.6 for SOD-mimetic assays; acetate or phosphate at pH 5–6 for certain peroxidase-like reactions. Avoid very strong base which can demetallate porphyrins over time.
Chloride control: Because axial chloride ligation affects spectra and activity, maintain a defined NaCl concentration (e.g., 50–150 mM) when reproducibility is critical. Report ionic strength.
Stock solutions: prepare a concentrated aqueous stock (e.g., 1–10 mM) in deionized water or buffer, filter (0.22 μm) if particles are observed. Protect from light. Verify concentration by UV–Vis using appropriate extinction coefficients for the chosen medium.
Compatibility: buffers containing strong coordinating anions (phosphate, imidazole, azide) can alter axial ligation and kinetics—validate in your assay context. Avoid azide in peroxidase-like reactions where it can act as an inhibitor/scavenger.
Metal chelators: EDTA/EGTA may weakly interact with Mn centers; effects are generally modest for metallated porphyrins but should be assessed case-by-case.

Item-specific buffer specs (pH range, conductivity, stabilizers): Not specified for this item; refer to CoA/Spec Sheet.

Green Alternatives

Perspective: MnTMPyP pentachloride is itself a catalyst. Using catalytic rather than stoichiometric quantities of redox reagents can improve process mass intensity and reduce waste. For aqueous-phase oxidations or redox control, consider the following options and tradeoffs.

Comparison (literature context; not product specifications):

Option: MnTMPyP (this product)
- Pros: highly water-soluble; operates in aqueous media; strong visible absorption for monitoring; cationic surface promotes substrate association in water.
- Cons: Manganese porphyrins can be sensitive to strong oxidants/bases; may require chloride control; potential ecotoxicity considerations for Mn-containing waste streams.
Alternative: MnTBAP (tetra(4-benzoate)porphyrin) or Fe/Ti porphyrin catalysts
- Pros: Different charge profile (anionic/neutral) may reduce nonspecific binding; some systems effective with green oxidants (H2O2, O2).
- Cons: Often less water-soluble; may require organic co-solvents.
Alternative: Organocatalysts for ROS modulation (e.g., nitroxyl radicals like TEMPO derivatives)
- Pros: Metal-free; amenable to aqueous media in some cases.
- Cons: Different selectivity; may be consumed stoichiometrically; UV–Vis tracking less straightforward.

Greener practice tips:

Favor water or water–ethanol co-solvents; avoid halogenated solvents.
Use H2O2 or O2 as terminal oxidants where compatible; avoid chlorinated oxidants if not necessary.
Implement catalyst recovery where feasible (e.g., immobilization on solid supports) and manage Mn-containing waste responsibly.

Pharmaceutical Uses

No pharmacopeial status or excipient role is provided for this product. This material is supplied strictly for research use only and is not intended for human or veterinary applications.

General formulation-related notes (literature context; not product specifications):

Role in formulations: Cationic metalloporphyrins like MnTMPyP are occasionally explored as analytical reagents or process research tools due to their strong chromophores and redox activity, rather than as excipients. They can serve as optical standards or catalytic additives in in vitro assays.
Solubility and vehicle: Readily dissolves in water and many aqueous buffers, which facilitates incorporation into test articles for pre-formulation or analytical method development studies. Organic co-solvents (e.g., small fractions of MeOH) may assist in preparing highly concentrated standards.
Stability considerations: Protect solutions from prolonged light exposure; maintain neutral to mildly acidic pH; avoid strong oxidants/reductants that could alter oxidation state or degrade the macrocycle.

Regulatory and quality:

Pharmacopeia listings: None indicated. Not specified for this item; refer to CoA/Spec Sheet if any compendial references exist.
Documentation: For any GLP/GMP-adjacent research, obtain and file the lot-specific CoA and SDS. Define and qualify analytical methods (UV–Vis, HPLC) used to track the compound in your processes.

Physical Properties

Item-specific physicochemical specifications (this lot):

Appearance: Not specified for this item; refer to CoA/Spec Sheet.
Molecular weight: Not specified for this item; refer to CoA/Spec Sheet.
Molecular formula: Not specified for this item; refer to CoA/Spec Sheet.
Other analytical limits (e.g., metals, UV cutoff, water): Not specified for this item; refer to CoA/Spec Sheet.

General/literature properties for MnTMPyP-type pentachloride salts (for context only; not product specifications):

Physical state: hygroscopic, deeply colored solid (typically green-red hue depending on oxidation state and ligand field)
Solubility: highly soluble in water and aqueous buffers; soluble in polar protic/aqueous-organic mixtures (e.g., water–methanol); limited solubility in nonpolar solvents
UV–Vis (literature, aqueous): intense Soret band in the ~450–470 nm region for Mn(III) porphyrins; Q-bands weaker and shifted relative to free-base porphyrins
Redox behavior: Mn(III)/Mn(II) couple accessible; axial ligation and pH influence spectra and redox potentials
pH stability (qualitative): generally stable in neutral to mildly acidic aqueous media; strong base or strong oxidants/reductants can alter oxidation state or degrade the macrocycle

Handling notes (general): solutions are strongly colored; absorbance can be used to estimate concentration using literature extinction coefficients specific to the complex and solvent. Always confirm extinction coefficients for your solvent/ionic strength before quantitative use.

Quality and Grades

Grade/Purity: Not specified for this item; refer to CoA/Spec Sheet.

Interpretation and expectations (general guidance):

Porphyrin salts such as MnTMPyP pentachloride are typically qualified by HPLC/UPLC purity, UV–Vis spectral conformity (Soret/Q-band positions and intensity ratios), and counterion content (chloride assay). Some suppliers also report residual metal contaminants and water content (Karl Fischer). None of these metrics are specified here—consult the CoA for the supplied lot.
Stabilizers: Not indicated for this item. Many porphyrin salts are provided neat without stabilizers; if present, stabilizers or residual salts (e.g., NaCl) will be disclosed on the CoA.
Batch-to-batch considerations: Porphyrins can differ in residual solvent/water content and degree of axial ligation. Verify extinction coefficients in your assay medium and, if necessary, convert to a defined axial ligand state before use (e.g., by adding Cl− or adjusting pH/ionic strength).
Suggested incoming QC (user): record UV–Vis spectrum in intended buffer, verify Soret position; optional ESI-MS for molecular ion cluster; chloride content by argentometric titration if needed; functional assay (e.g., redox activity) appropriate to application.
Compliance: This product is for research use only and not intended for diagnostic or therapeutic use.

Reaction and Applications

Manufacturer applications: Not provided. The following summarizes established research uses of MnTMPyP-type complexes (literature context; not item-specific claims):

Redox catalysis/Radical chemistry: MnTMPyP(Cl) porphyrins function as catalytic mimics of superoxide dismutase in vitro by cycling between Mn(III)/Mn(II) states, facilitating disproportionation of superoxide. They can also catalyze decomposition of peroxynitrite and react with hydrogen peroxide in ligand- and pH-dependent pathways.
Oxidation catalysis: Employed as homogeneous catalysts for selective oxidations (e.g., epoxidation, hydroxylation) using oxidants such as iodosylbenzene, NaClO, or H2O2 in aqueous or mixed media. Cationic periphery enhances activity in water and interaction with polar substrates.
Spectroscopic probe/standard: Strong Soret absorption and well-defined redox transitions make MnTMPyP useful for method development in UV–Vis and electrochemical studies. Often used as a standard for porphyrin spectral calibration.
Nucleic acid/protein interaction studies: The tetracationic periphery promotes electrostatic association with polyanions, enabling biophysical studies of binding and electron-transfer processes.

Practical tips:

Control chloride concentration; axial ligation to Mn affects catalytic profile and Soret position. Adding NaCl can standardize speciation prior to assays.
Degas or oxygenate solutions depending on desired redox pathways. Use amber glassware or foil wrap to limit photochemistry.
Verify concentration by UV–Vis using literature ε values appropriate to solvent/ionic strength; avoid assuming values from free-base porphyrins.

Reaction Conditions

Representative conditions from the literature for Mn(III) porphyrin catalysis (guidance only; optimize for your system):

Epoxidation of alkenes:
- Catalyst: MnTMPyP (0.1–2 mol%)
- Oxidant: NaClO (household bleach, pH-adjusted) or iodosylbenzene; alternatives include H2O2 with appropriate co-catalyst/base
- Solvent: water–acetonitrile (1:1 to 4:1) or water–methanol; temperature 0–25°C
- Notes: control pH ~7–9 depending on oxidant; chloride concentration influences speciation. Monitor by GC or HPLC.
Benzylic/allylic oxidation:
- Catalyst: 0.5–5 mol%
- Oxidant: H2O2 (30%) with bicarbonate or phosphate buffer; 10–40°C
- Notes: slow addition of H2O2 limits over-oxidation; verify catalyst stability by UV–Vis during reaction.
Peroxidase-like transformations:
- Substrates: ABTS, TMB, or guaiacol as chromogenic probes
- Conditions: aqueous buffer (pH 5–7), H2O2 as oxidant, μM catalyst levels
- Readout: monitor absorbance changes of oxidized dyes.
SOD-mimetic assays (cell-free):
- Systems: xanthine/xanthine oxidase or KO2-derived O2•− generation
- Buffer: phosphate or HEPES (pH ~7.4) with defined ionic strength (e.g., 100 mM NaCl)
- Notes: quantify by inhibition of cytochrome c reduction or WST-1 formazan formation; calibrate using known standards.

These conditions are illustrative; solvent, temperature, and oxidant must be tailored to substrate, desired selectivity, and safety constraints. Always perform small-scale trials and verify catalyst speciation in your medium.

Safety and Handling

Authoritative hazard classification for this specific item has not been provided. Always consult the product SDS for definitive GHS classification, pictograms, signal word, and H/P statements.

GHS classification, signal word, pictograms, H-statements: Not specified for this item; refer to SDS.

General laboratory safety guidance for manganese porphyrin chloride salts:

Potential hazards: cationic porphyrins are strongly colored, can stain; manganese complexes are redox-active and may catalyze oxidation of organic material in solution. Dust may be irritating. Avoid inhalation and contact with skin/eyes.
PPE: lab coat, safety glasses or face shield, and appropriate chemical-resistant gloves (e.g., nitrile). Work in a fume hood when weighing powders or handling concentrated solutions.
Incompatibilities: avoid strong oxidizers and strong reducing agents (uncontrolled redox); avoid strong bases/acids that can demetallate or degrade the macrocycle. Chlorinating agents may alter axial ligation and speciation.
Handling: minimize exposure to light to reduce photochemical reactions; prepare fresh aqueous solutions when feasible. Use clean, oxygenated or deoxygenated buffers as required by your assay; the complex can participate in ROS/RNS chemistry.
First aid (summary): skin/eye contact—rinse with water for at least 15 minutes; inhalation—move to fresh air; ingestion—rinse mouth, seek medical attention. Provide SDS to responders.
Waste: dispose of solutions and contaminated materials as hazardous chemical waste per institutional and local regulations.
Transport: ship as supplied; this item is shipped in an ice chest with ice pads per listing.

Solvent Selection

MnTMPyP pentachloride is a highly cationic porphyrin complex designed for aqueous use.

General/literature solvent behavior (not item specifications):

Polarity/miscibility: readily soluble in water and common aqueous buffers (e.g., PBS, phosphate, HEPES); miscible upon dilution with polar protic solvents (water–MeOH, water–EtOH) and some polar aprotics (MeCN) when water is present. Poorly soluble in nonpolar organics.
Dielectric considerations: high dielectric solvents (water, MeOH) favor dissociation of chloride counterions and modulate axial ligation and redox potential. Ionic strength (Cl− concentration) can shift spectra and speciation.
When to choose water vs mixed solvents:
- Pure aqueous buffers for biochemical assays (ROS/RNS scavenging, redox catalysis)
- Water–MeOH or water–MeCN for analytical work (HPLC detection, spectral calibration) or for organic oxidations where small organic co-solvent improves substrate solubility
pH control: neutral to mildly acidic buffers commonly used. Avoid strong base that can demetallate or alter macrocycle integrity.

Comparison (general):

MnTMPyP vs MnTBAP (tetra-4-benzoate): MnTMPyP is more water-soluble (cationic) and interacts more with polyanions (e.g., DNA, proteins), whereas MnTBAP is anionic and may have different binding profiles. Selection depends on matrix interaction needs and ionic environment.

Storage and Reconstitution

Storage conditions (as provided): Store at −20°C. Shipments are made in an ice chest with ice pads.
Light and atmosphere: Protect solids and solutions from light (amber vial or foil wrap). Store under dry conditions; use a desiccant to minimize moisture uptake. Avoid prolonged exposure to air in solution to limit unintended redox changes, unless required by your assay.
Stability (general guidance; not item-specific specs): Dry solid is typically stable for many months at −20°C when protected from light and moisture. Aqueous solutions are best prepared fresh; if necessary, aliquot and store at 2–8°C for short terms (days) or at −20°C for longer terms (weeks), avoiding repeated freeze–thaw.
Reconstitution: Bring vial to room temperature in a desiccator before opening to prevent condensation. Dissolve in ultrapure water or desired buffer to prepare a concentrated stock (e.g., 1–10 mM). Gently mix until homogeneous; do not sonicate excessively to avoid heating.
Working solutions: Prepare immediately prior to use. Verify concentration by UV–Vis (Soret band). Adjust ionic strength (e.g., NaCl) consistently across experiments to standardize axial ligation.
Compatibility: Avoid strong bases/acids, strong oxidants/reductants that can demetallate or bleach the porphyrin. Use clean glassware; avoid residual bleach or peroxides unless intended.
Labeling: Record preparation date, solvent, pH, and estimated concentration on all stock and working vials.

Item-specific stabilizers, shelf-life, and solution stability data: Not specified for this item; refer to CoA/Spec Sheet.

Structure and Identity

MnTMPyP pentachloride is a manganese(III) porphyrin bearing four N-methyl-4-pyridinium (TMPyP) meso substituents; the cationic porphyrin framework is typically balanced by five chloride anions (one often serving as an axial ligand to Mn). The macrocycle is a planar, conjugated porphyrin ring with the manganese center coordinated by the four porphyrin nitrogens; para-substituted pyridinium groups extend from each meso position, each bearing an N-methyl substituent to confer permanent positive charge and high water solubility.

SKU: M342517; Product name: MnTMPyP pentachloride
CAS: 100012-18-8; PubChem CID: 216239
Category: Chemistry & Biochemical Reagents (research use only)
Molecular formula: Not specified for this item; refer to CoA/Spec Sheet.
Molecular weight: Not specified for this item; refer to CoA/Spec Sheet.
SMILES: Not specified for this item; refer to CoA/Spec Sheet.
InChIKey: Not specified for this item; refer to CoA/Spec Sheet.

Structural features (general/literature):

Core: metalloporphyrin (porphine dianion coordinated to Mn(III))
Substituents: four para-pyridinium rings, each N-methylated (quaternary ammonium)
Charge: highly cationic complex; typically isolated as a pentachloride salt
Axial ligation: Mn(III) often bears an axial chloride in chloride media; axial coordination is labile in water and buffers

2D description in words (general): a central Mn within a planar tetrapyrrolic ring; at each meso carbon, a para-pyridinium ring extends outward; each pyridine nitrogen is methylated, giving a symmetric, tetracationic porphyrin macrocycle paired with chloride counterions.

Synthetic Utility

While MnTMPyP pentachloride is most often used in aqueous redox and biophysical studies, it is also a valuable homogeneous catalyst in synthetic chemistry (literature context; not item specifications):

Oxidation reactions: Mn(III) porphyrins catalyze epoxidation and allylic/benzylic oxidation using oxidants such as iodosylbenzene, NaClO, or H2O2. The cationic periphery promotes activity in water and can influence substrate orientation via electrostatic interactions.
Oxygen-transfer mechanisms: Typically proceed via high-valent Mn=O (oxo) or Mn–OOH intermediates; axial ligands (Cl−, imidazole, pyridine) tune reactivity and selectivity. Electron-deficient, cationic porphyrins often stabilize higher-valent states conducive to oxygen transfer.
Phase and media: Activity in aqueous or biphasic systems enables greener protocols. Mixed solvents (water–acetonitrile or water–alcohol) can balance substrate solubility and catalyst stability.
Selectivity control: Choice of axial base, oxidant, and ionic strength allows tuning between epoxidation vs. hydroxylation. Substrate and catalyst concentrations should be optimized to minimize over-oxidation.
Recovery/reuse: Though homogeneous, MnTMPyP can be immobilized on ionic supports (e.g., ion-exchange resins) for simplified separation and reuse in flow or batch.

Practical consideration: Verify catalyst integrity by UV–Vis before and after reaction (Soret/Q-band retention). Excess oxidant or high pH can bleach the porphyrin; use controlled addition and buffered conditions.

Target Specificity

This product is a small-molecule manganese porphyrin complex, not an antibody, enzyme, or oligonucleotide. Therefore, immunological target specificity (antigen/epitope, clone, isotype, species reactivity) is not applicable.

Target/epitope details: Not applicable.
Tested reactivity panels: Not applicable.

For users seeking biological selectivity information: cationic MnTMPyP complexes exhibit physicochemical preferences (e.g., electrostatic association with polyanions) rather than specific molecular recognition. Any observed selectivity in assays typically arises from charge, axial ligation, and local environment rather than lock-and-key binding to a defined biomolecular epitope.

Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

Lot Number	Certificate Type	날짜	항목
D23031201	Certificate of Analysis	Jan 21, 2026	M342517
D23031233	Certificate of Analysis	Jan 21, 2026	M342517
D23031240	Certificate of Analysis	Jan 21, 2026	M342517
D23031247	Certificate of Analysis	Jan 21, 2026	M342517
D23031187	Certificate of Analysis	Mar 24, 2023	M342517
D23031202	Certificate of Analysis	Mar 24, 2023	M342517

용해성	Soluble in water, 0.1M TRIS-HCl, pH 9.0 containing 1mM EDTA (>50 mg/ml), and PBS, pH 7.2 (4 mg/ml).
분자량	464.800 g/mol
XLogP3	4.100
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Exact Mass	464.086 Da
Monoisotopic Mass	464.086 Da
Topological Polar Surface Area	92.400 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	646.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

MnTMPyP pentachloride - ≥95% , CAS No.100012-18-8