MU1210 , CAS No.2275601-87-9

CAS: 2275601-87-9 Cat. No.: M1425991 PubChem CID: 155891794

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

MU1210 (compound 12f) is an inhibitor of CDC-like kinases Clk1 , Clk2 , and Clk4 (with IC 50 values of 8, 20, and 12 nM respectively), with IC 50 for HIPK1 and DYRK2 are 187 and 1309 nM. MU1210 also has favorable pharmacokinetic characteristics (in mice, 10 mg/kg, intraperitoneal injection: C max =1.24 μM, T 1/2 =58 minutes; no acute toxicity observed).

사양

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

INHIBITOR

이름과 식별자

정식 스마일

CN1C=C(C=N1)C2=NC3=C(C=C2)OC=C3C4=CC=CC(=C4)C5=CC=NC=C5

IUPAC Name

5-(1-methylpyrazol-4-yl)-3-(3-pyridin-4-ylphenyl)furo[3,2-b]pyridine

InChIKey

HEAGNKNMQVIVMM-UHFFFAOYSA-N

INCHI

1S/C22H16N4O/c1-26-13-18(12-24-26)20-5-6-21-22(25-20)19(14-27-21)17-4-2-3-16(11-17)15-7-9-23-10-8-15/h2-14H,1H3

이성체 SMILES

CN1C=C(C=N1)C2=NC3=C(C=C2)OC=C3C4=CC=CC(=C4)C5=CC=NC=C5

PubChem CID

155891794