MUC1 Mouse mAb - 1차 항체, specific to MUC1, Mouse IgG1

Cat. No.: Ab116370

등급 & 순도 Carrier Free, ExactAb™, Azide Free, Validated, High Performance, See COA

Application

WB

Host species

마우스

Reactive species

인간

Isotype

Mouse IgG1

Clone Number

C1

Conjugation

Unconjugated

개요

Mouse anti Human MUC1 antibody; , Monoclonal (C1), could be used for WB and so on.
Application:
WB: 0.01-2 µg/mL
Protein Function
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

사양

Product Name

MUC1 Mouse mAb - 1차 항체, specific to MUC1, Mouse IgG1

동의어

ADMCKD antibody | ADMCKD1 antibody | Breast carcinoma associated antigen DF3 antibody | Breast carcinoma-associated antigen DF3 antibody | CA 15-3 antibody | CA15 3 antibody | CA15 3 antigen antibody | CA15-3 antibody | CA15.3 antibody | Cancer antigen 15

사양 및 순도

Carrier Free, ExactAb™, Azide Free, Validated, High Performance, See COA

숙주 종

마우스

특이성

MUC1

면역원

Recombinant MUC1 expressed in E.coli (AA 1034~1151)

포지티브 제어

WB: Human milk.

변화

Unconjugated

등급

Azide Free, Carrier Free, ExactAb™, High Performance, Validated

아이소타입

Mouse IgG1

라이트 체인 유형

kappa

SDS-PAGE

150 kDa

정화 방법

Protein A + Protein G affinity purified

집중력

See COA

Product Line

생물 제품

보관 및 배송

모양

Liquid

보관 조건

Store at -20°C,Avoid repeated freezing and thawing

배송

Ice chest + Ice pads

안정성 및 스토리지

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

이미지

Western Blot: MUC1 Mouse mAb (Ab116370)

MUC1 Mouse mAb (Ab116370) - Western Blot
All lanes: MUC1 Mouse mAb (Ab116370) at 1/3000 dilution
Samples: Human milk
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 25 kDa
Observed band size: 23,19 kDa
Exposure time: 10.0 s

적용

적용

Dilution info

WB

0.01-2 µg/mL

관련 대상(인간)

MUC1 Tchem Mucin-1 (0 Activities)

Discover Target: MUC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

작용 메커니즘

자주 묻는 질문

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (MUC1 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.